High prevalence of peripheral arterial disease and co-morbidity in 6880 primary care patients: cross-sectional study
High prevalence of peripheral arterial disease and co-morbidity in 6880 primary care patients: cross-sectional study
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DOI：
10.1016/s0021-9150(03)00204-1
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发表时间：
2004-01-01
期刊：
影响因子：
5.3
通讯作者：
Trampisch, HJ
中科院分区：
文献类型：
--
作者：
Diehm, C;Schuster, A;Trampisch, HJ
我们的目的是获得一般医疗实践中外周动脉疾病（PAD）的流行病学、合并症和危险因素概况的可靠数据。在德国踝臂指数观察性流行病学试验（getABI 研究）的横断面部分中，德国各地的 344 名全科医生通过双侧多普勒超声测量确定了连续未选择的 65 岁或以上患者的 ABI。其他评估包括患者病史，重点是动脉粥样硬化血栓性疾病和体格检查。以及世界卫生组织关于间歇性跛行的调查问卷。总共纳入 6880 名患者（42.0% 为男性，平均年龄 72.5 岁，平均体重指数 27.3 kg/m(2)，平均收缩压/舒张压 143.7/81.3 mmHg）。以踝臂指数 (AB1) < 0.9 表示的男性/女性 PAD 患病率为 19.8/16.8%。患有 PAD 的患者比无 PAD 的患者年龄稍大，更容易患糖尿病（36.6% vs. 22.6%；调整后的 OR：1.8）、高血压（78.8 vs. 61.6%；OR：2.2）、血脂紊乱（57.2 vs. 50.7%；OR：1.3）和其他共存的动脉粥样硬化性疾病（任何脑血管事件：15.0 vs. 1.3）。 7.6%；OR：1.8；任何心血管事件：28.9 vs. 17.0%；这些数据突显了初级保健中 PAD 的高患病率。 PAD 患者的共同发病率较高，尤其是动脉粥样硬化血栓形成的其他表现。用于 ABI 测定的多普勒超声测量是初级保健中一种无创、廉价、可靠的工具，使全科医生能够识别有 PAD 风险的患者。 (C) 2003 Elsevier Ireland Ltd. 保留所有权利。
We aimed to obtain reliable data on the epidemiology, co-morbidities and risk factor profile of peripheral arterial disease (PAD) in general medical practise. In the cross-sectional part of the observational German Epidemiological Trial on Ankle Brachial Index (getABI study), 344 general practitioners throughout Germany determined the ABI of consecutive, unselected patients aged 65 years or older with bilateral Doppler ultrasound measurements. Additional assessments comprised patient history with the focus on atherothrombotic diseases, physical examination. and the WHO questionnaire on intermittent claudication. A total of 6880 patients were included (42.0% male, mean age 72.5 years, mean body mass index 27.3 kg/m(2), mean systolic/diastolic blood pressure 143.7/81.3 mmHg). The prevalence of PAD for men/women as indicated by an ankle brachial index (AB1) < 0.9 was 19.8/16.8%. Patients with PAD were slightly older than patients without PAD, suffered more frequently from diabetes (36.6 vs. 22.6%; adjusted OR: 1.8), hypertension (78.8 vs. 61.6%; OR: 2.2), lipid disorders (57.2 vs. 50.7%; OR: 1.3) and other coexisting atherothrombotic diseases (any cerebrovascular event: 15.0 vs. 7.6%; OR: 1.8; any cardiovascular event: 28.9 vs. 17.0%; OR: 1.5). The data highlight the high prevalence of PAD in primary care. PAD patients are characterised by a high co-morbidity, particularly with regard to other manifestations of atherothrombosis. Doppler ultrasound measurement for ABI determinations is a non-invasive, inexpensive, reliable tool in primary care and enables GPs to identify patients at risk of PAD. (C) 2003 Elsevier Ireland Ltd. All rights reserved.