Mucoepidermoid carcinoma of the parotid gland
Mucoepidermoid carcinoma of the parotid gland
复制标题
腮腺粘液表皮样癌
DOI：
10.1002/1097-0142(196807)22:1
复制
发表时间：
1968
期刊：
影响因子：
6.2
通讯作者：
C. Eneroth
中科院分区：
文献类型：
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作者：
P. Jakobsson;C. Blanck;C. Eneroth
在对1678例腮腺肿瘤进行的组织学复查和重新分类中，63例（3.7%）显示出粘液表皮样癌的特征性结构。一项长期随访研究表明，粘液表皮样癌与腺泡细胞癌和腺样囊性癌的不同之处在于，当随访超过5年时，确定的生存率不会显著下降。这意味着可以在5年随访研究后评估基于确定生存率的预后。在组织学上，63个肿瘤被分为两个亚组，一个亚组由20个表现出浸润性生长的肿瘤（高度恶性）组成，另一个亚组由43个没有浸润性生长的肿瘤（低度恶性）组成。随访研究显示两组预后差异。为改善高度恶性粘液表皮样癌的不良预后，作者建议对高度恶性粘液表皮样癌应常规行腮腺切除联合颈淋巴结清扫术。
In a histologic re‐examination and reclassification of a series of 1678 tumors of the parotid gland, 63 (3.7%) exhibited the structures characteristic of mucoepidermoid carcinoma. A long‐term follow‐up study showed that mucoepidermoid carcinoma differs from acinic cell and adenoid cystic carcinoma in that the determinate survival rate does not fall markedly when the follow‐up exceeds 5 years. This implies that the prognosis based on the determinate survival rate can be evaluated after a 5‐year follow‐up study. Histologically, the 63 tumors have been divided into two subgroups, one consisting of 20 tumors exhibiting invasive growth (high grade malignant) and the other of 43 without invasive growth (low grade malignant). The follow‐up study showed the difference between the prognosis in the two groups. In order to improve the poor prognosis in high grade malignant mucoepidermoid carcinoma, the authors recommend that parotidectomy should be routinely combined with radical neck dissection in high grade malignant tumors.