Anti-inflammatory cytokines in endometriosis
Anti-inflammatory cytokines in endometriosis
复制标题
子宫内膜异位症中的抗炎细胞因子
DOI：
10.1007/s00018-019-03056-x
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发表时间：
2019
影响因子：
8
通讯作者：
Li Ming Qing
中科院分区：
文献类型：
--
作者：
Zhou Wen Jie;Yang Hui Li;Shao Jun;Mei Jie;Chang Kai Kai;Zhu Rui;Li Ming Qing
Although the pathogenesis of endometriosis is not fully understood, it is often considered to be an inflammatory disease. An increasing number of studies suggest that differential expression of anti-inflammatory cytokines (e.g., interleukin-4 and -10, and transforming growth factor-β1) occurs in women with endometriosis, including in serum, peritoneal fluid and ectopic lesions. These anti-inflammatory cytokines also have indispensable roles in the progression of endometriosis, including by promoting survival, growth, invasion, differentiation, angiogenesis, and immune escape of the endometriotic lesions. In this review, we provide an overview of the expression, origin, function and regulation of anti-inflammatory cytokines in endometriosis, with brief discussion and perspectives on their future clinical implications in the diagnosis and therapy of the disease.
