Vaticanol C, a novel resveratrol tetramer, inhibits cell growth through induction of apoptosis in colon cancer cell lines

Vaticanol C, a novel resveratrol tetramer, inhibits cell growth through induction of apoptosis in colon cancer cell lines
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DOI:
10.1248/bpb.25.147
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发表时间:
2002-01-01
影响因子:
2
通讯作者:
Nozawa, Y
Nozawa, Y
中科院分区:
医学4区
文献类型:
--
作者:
Ito, T;Akao, Y;Nozawa, Y

文献摘要

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一种新的白藜芦醇四聚体,vaticanol C,从青皮茎树皮中分离出显着抑制细胞生长,通过诱导细胞凋亡,其特征在于核的变化和DNA梯形的形成,在三个不同的人结肠癌细胞系。
A novel resveratrol tetramer, vaticanol C, isolated from the stem bark of Vatica rassak markedly suppressed cell growth through induction of apoptosis, which was characterized by nuclear changes and DNA ladder formation, in three different human colon cancer cell lines.