Efficacy of risk-reduction counseling to prevent human immunodeficiency virus and sexually transmitted diseases - A randomized controlled trial

Efficacy of risk-reduction counseling to prevent human immunodeficiency virus and sexually transmitted diseases - A randomized controlled trial
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DOI:
10.1001/jama.280.13.1161
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发表时间:
1998-10-07
影响因子:
120.7
通讯作者:
Peterman, TA
Peterman, TA
中科院分区:
医学1区
文献类型:
--
作者:
Kamb, ML;Fishbein, M;Peterman, TA

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背景。-咨询,以防止感染人类免疫缺陷病毒(艾滋病毒)和其他性传播疾病(性病)的有效性还没有得到明确的显示。比较2个交互式艾滋病毒/性病咨询干预措施的效果与典型的教学预防信息的现行做法。多中心随机对照试验(Project ECOECT),患者被分配到3个单独的面对面干预中的1个。1993年7月至1996年9月期间,五家公共性病诊所(马里兰州巴尔的摩;丹佛,科尔;加利福尼亚州长滩;新泽西州纽瓦克;加利福尼亚州旧金山弗朗西斯科)。共有5758名14岁或以上的异性恋艾滋病毒阴性患者前来接受性病检查。第1组接受强化咨询,4次互动理论课程。第2组接受了简短的咨询,2次互动式风险降低会议。第3组和第4组各接受2条当前护理的典型简短教育信息。入组后,在第3、6、9和12个月进行问卷调查,并在第6和12个月进行STD检查,对第1、2和3组进行积极随访。意向治疗分析用于比较干预措施。自我报告的安全套使用和新的性病诊断(淋病,衣原体,梅毒,艾滋病毒)通过实验室测试定义。在3个月和6个月随访访视时!自报100%安全套使用率高于对照组(P
Context.-The efficacy of counseling to prevent infection with the human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs) has not been definitively shown.Objective.-To compare the effects of 2 interactive HIV/STD counseling interventions with didactic prevention messages typical of current practice.Design.-Multicenter randomized controlled trial (Project RESPECT), with par ticipants assigned to 1 of 3 individual face-to-face interventions.Setting.-Five public STD clinics (Baltimore, Md; Denver, Cole; Long Beach, Calif; Newark, NJ; and San Francisco, Calif) between July 1993 and September 1996.Participants.-A total of 5758 heterosexual, HIV-negative patients aged 14 years or older who came for STD examinations.Interventions.-Arm 1 received enhanced counseling, 4 interactive theory based sessions. Arm 2 received brief counseling, 2 interactive risk-reduction sessions. Arms 3 and 4 each received 2 brief didactic messages typical of current care. Arms 1, 2, and 3 were actively followed up after enrollment with questionnaires at 3, 6, 9, and 12 months and STD tests at 6 and 12 months. An intent-to-treat analysis was used to compare interventions.Main Outcome Measures.-Self-reported condom use and new diagnoses of STDs (gonorrhea, chlamydia, syphilis, HIV) defined by laboratory tests.Results.-At the 3- and 6-month follow-up visits! self-reported 100% condom use was higher (P