The effect of splanchnic sympathectomy in hypertensive patients upon estimated hepatic blood flow in the upright as contrasted with the horizontal position.
The effect of splanchnic sympathectomy in hypertensive patients upon estimated hepatic blood flow in the upright as contrasted with the horizontal position.
复制标题
高血压患者内脏交感神经切除术对直立位与水平位相比估计肝血流量的影响。
DOI：
10.1172/jci102446
复制
发表时间：
1951
期刊：
影响因子：
--
通讯作者：
F. Ingelfinger
中科院分区：
文献类型：
--
作者：
R. Wilkins;J. W. Culbertson;F. Ingelfinger
已经发现，当血压正常或高血压受试者被动地倾斜到直立位置时，估计的肝血流量（EHBF）（2）减少，计算的肝门静脉阻力（HPR）增加（3）。这些变化被认为是由于主动内脏血管收缩，可能通过内脏交感神经系统介导。在一些接受内脏交感神经切除术的高血压患者中，可以获得与这一假设有关的直接证据，随后采用与术前相同的方法进行研究。这些研究是本报告的基础。
It has been found that when normotensive or hypertensive subjects are tilted passively into an upright position estimated hepatic blood flow (EHBF) (2) decreases and calculated hepatic portal resistance (HPR) increases (3). These changes were assumed to be due to active splanchnic vasoconstriction, probably mediated over the splanchnic sympathetic nervous system. Direct evidence bearing on this assumption became available in some of the hypertensive patients undergoing splanchnic sympathectomy and subsequently studied by the same methods as before operation. Such studies are the basis of the present report.