Effects of Samso-Eum on cytokine productions in asthmatic mice
Effects of Samso-Eum on cytokine productions in asthmatic mice
复制标题
Samso-Eum 对哮喘小鼠细胞因子产生的影响
DOI：
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
Suin Cho
中科院分区：
文献类型：
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作者：
Hyung;S. Cho;Bu;Jin;H. Jeong;Suin Cho
Objective : The application of Sam So Eum (蔘蘇飮, SSE) as a herbal medicine to treat asthma in mice has been studied and the mechanism of cytokine production in asthmatic mice was discussed. Recently, SSE was known to have anti-allergic activity. However, its therapeutic mechanisms are unclear. Methods : So, we investigated the effects of SSE on levels of several cytokines in bronchoalveolar lavage fluid (BALF) using flow cytometric analysis in allergen-induced asthma. Results : In this experiment, SSE decreased levels of IL-la, IL-17 and GM-CSF respectively. Contrary, SSE restored level of IFN-g toward naive level in BALF. Conclusion : In conclusion, we demonstrate that SSE is useful to treat asthma and it's therapeutic mechanisms are involved in Thl skewing reaction.