Validation of a Portable Monitoring System for the Diagnosis of Obstructive Sleep Apnea Syndrome
Validation of a Portable Monitoring System for the Diagnosis of Obstructive Sleep Apnea Syndrome
复制标题
DOI：
10.1093/sleep/32.5.629
复制
发表时间：
2009-05-01
期刊：
影响因子：
5.6
通讯作者：
Bittencourt, Lia R. A.
中科院分区：
文献类型：
--
作者：
Santos-Silva, Rogerio;Sartori, Denis E.;Bittencourt, Lia R. A.
研究目的：评估便携式监测仪能否准确测量疑似阻塞性睡眠呼吸暂停（OSA）患者的呼吸暂停低通气指数（AHI）。设计：前瞻性随机。设定：睡眠实验室。参与者：80名参与者：干预：N/A测量和结果：进行三阶随机评估：（1）在参与者家中使用STD（Stardust II）（STD家庭），（2）在睡眠实验室中与PSG同时使用STD（STD+PSG实验室），和（3）在没有STD的情况下进行PSG（PSG实验室）。生成并分析了四个AHI值：（a）STD家庭;（B）STD+PSG实验室的STD;（c）STD+PSG的PSG（命名为PSG+STD实验室）;和（d）PSG实验室。两名技术人员对研究详情设盲，对所有评价进行分析。对于所有4个AHI值，STD和PSG记录的AHI之间存在强相关性（所有相关性均高于0.87）。计算AHI临界值为5、15和30起事件/小时时的灵敏度、特异性以及阳性和阴性预测值。将PSG实验室和PSG+STD实验室的AHI值与STD家庭和STD+PSG实验室的AHI值进行了比较，结果显示STD和PSG同时进行时的结果最佳。在所有分析中，ROC曲线下面积至少为0.90。通过多重比较，诊断一致性在91%至75%之间。Bland Altman分析表明，AHI值从STD和PSG recording. Conclusion，特别是当比较AHI从同时STD和PSG recording.Conclusion：这些数据表明，STD是准确的，在确认诊断OSA的地方有一个怀疑的障碍。更好的协议发生在同时记录。
Study Objective: To evaluate if a portable monitor could accurately measure the apnea-hypopnea index (AHI) in patients with a suspicion of obstructive sleep apnea (OSA).Design: Prospective and randomized. Setting: Sleep laboratory.Participants: 80 participants: 70 patients with clinical OSA suspicion and 10 subjects without suspicion of OSA.Interventions: N/AMeasurements and Results: Three-order randomized evaluations were performed: (1) STD (Stardust II) used at the participants' home (STD home), (2) STD used simultaneously with PSG in the sleep lab (STD+PSG lab), and (3) PSG performed without the STD (PSG lab). Four AHI values were generated and analyzed: (a) STD home; (b) STD from STD+PSG lab; (c) PSG from STD+PSG (named PSG+STD lab); and (d) PSG lab. Two technicians, blinded to study details, performed the analyses of all evaluations. There was a strong correlation between AHI from the STD and PSG recordings for all 4 AHI values (all correlations above 0.87). Sensitivity, specificity, and positive and negative predictive values at AHI cut-off values of 5, 15, and 30 events/hour were calculated. AHI values from the PSG lab and PSG+STD lab were compared to STD home and STD+PSG lab and showed the best results when STD and PSG were performed simultaneously. In all analyses, the area under ROC curve was at least 0.90. With multiple comparisons, diagnostic agreement was between 91% and 75%. The Bland Altman analyses showed strong agreement between AHI values from the STD and PSG recordings, especially when comparing the AHI from simultaneous STD and PSG recordings.Conclusion: These data suggest that the STD is accurate in confirming the diagnosis of OSA where there is a suspicion of the disorder. Better agreement occurred during simultaneous recordings.