Tumor ablation: common modalities and general practices.
Tumor ablation: common modalities and general practices.
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DOI：
10.1053/j.tvir.2013.08.002
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发表时间：
2013-12
影响因子：
1.7
通讯作者：
Brace CL
中科院分区：
文献类型：
--
作者：
Knavel EM;Brace CL
肿瘤消融术是一种微创技术，常用于治疗肝、肾、骨和肺肿瘤。在肿瘤消融过程中，热能用于将组织加热或冷却至细胞毒性水平（低于-40 °C或高于60°C）。另一种技术正在开发中，其目标是细胞膜的渗透性，并且表面上是非热的。在肿瘤消融的分类中，有几种模式在世界范围内使用：射频、微波、激光、高强度聚焦超声、冷冻消融和不可逆电穿孔。每种技术虽然目的相似，但都有特定的最佳适应症。这篇综述讨论了一般原则和技术，回顾了每种模式，并讨论了模式的选择。
Tumor ablation is a minimally invasive technique that is commonly used in the treatment of tumors of the liver, kidney, bone, and lung. During tumor ablation, thermal energy is used to heat or cool tissue to cytotoxic levels (less than −40°C or more than 60°C). An additional technique is being developed that targets the permeability of the cell membrane and is ostensibly nonthermal. Within the classification of tumor ablation, there are several modalities used worldwide: radiofrequency, microwave, laser, high-intensity focused ultrasound, cryoablation, and irreversible electroporation. Each technique, although similar in purpose, has specific and optimal indications. This review serves to discuss general principles and technique, reviews each modality, and discusses modality selection.