Eukaryotic initiation factor 4E.
Eukaryotic initiation factor 4E.
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DOI:
10.1016/j.biocel.2007.10.023
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发表时间:
2008
影响因子:
4
通讯作者:
Roberts, Lisa O.
中科院分区:
文献类型:
--
作者:
Goodfellow, Ian G.;Roberts, Lisa O.
Eukaryotic translation initiation factor 4E (eIF4E) is perhaps best known for its function in the initiation of protein synthesis on capped mRNAs in the cytoplasm. However, recent studies have highlighted that eIF4E has many additional functions, which include the nuclear export of specific mRNAs as well as roles in ageing and the translation of some uncapped viral RNAs. This review aims to update the reader on recent developments, including the potential of eIF4E as a therapeutic target.
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影响因子:
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发表时间:
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影响因子:
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