Peptidergic input to immunohistochemically-identified Renshaw cells
Peptidergic input to immunohistochemically-identified Renshaw cells
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DOI：
10.1016/s0006-8993(00)03059-6
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发表时间：
2000-12-22
期刊：
影响因子：
2.9
通讯作者：
Zaruba, RA
中科院分区：
文献类型：
--
作者：
Carr, PA;Roller, MJ;Zaruba, RA
以大鼠Renshaw细胞特异性标志物--吉菲林免疫反应性为指标，结合P物质、降钙素基因相关肽和烟碱型乙酰胆碱受体免疫标记技术，评价多肽对大鼠Renshaw细胞的影响。平均每个Renshaw细胞有3.9个P物质和8.1个降钙素基因相关肽，16.3个烟碱型乙酰胆碱受体免疫反应阳性的密切接触或点状突起。大多数对置词是体细胞的。这些结果为Renshaw细胞的肽能调节提供了神经解剖学支持。(C)2000 Elsevier Science B.V.保留所有权利。
Peptidergic influences on Renshaw cells were assessed in rat using gephyrin-immunoreactivity, as a Renshaw cell specific marker, in combination with substance P, calcitonin gene-related peptide- and nicotinic acetylcholine receptor-immunolabelling. An average of 3.9 substance P-, and 8.1 calcitonin gene-related peptide-, and 16.3 nicotinic acetylcholine receptor-immunoreactive close contacts or puncta were observed per Renshaw cell. Most appositions were somatic. These results provide neuroanatomical support for the peptidergic modulation of Renshaw cells. (C) 2000 Elsevier Science B.V. All rights reserved.