Chinese herbal medicine resources: Where we stand.
Chinese herbal medicine resources: Where we stand.
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DOI：
10.1016/j.chmed.2019.08.004
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发表时间：
2020-01
影响因子：
3.8
通讯作者：
中科院分区：
文献类型：
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作者：
近年来，中药资源的短缺和与终端产品相关的药物安全问题对中药的发展提出了挑战。通过对中药学代表性期刊《中草药》的调研，分析了中药学资源的研究趋势，揭示了我国学者为应对这些挑战所做的巨大努力。本研究以2013-2018年发表的781篇中药资源文献为研究对象，包括中药种质资源、中药品质分析与评价、中药栽培、中药生物工程四个主题领域。讨论并展望了今后的研究方向，包括：构建药用植物核心种质，拓展种质资源；将分子研究与田间试验相结合，促进中药材栽培的深入研究；改进中药材质量评价方法，加强中成药鉴定；利用生物工程和合成生物学促进中药材资源的可持续发展。本研究有助于国际学者了解中医药研究现状，为中医药的健康、现代、国际化发展提供理论支持，促进中医药产业的可持续发展。
In recent years, the development of Chinese herbal medicine (CHM) has been challenged by shortages of CHM resources and drug safety concerns related to end products. There have been significant efforts by Chinese scholars to tackle these challenges, which are revealed by analyzing the research trend of CHM resources via surveying Chinese Traditional and Herbal Drugs (Zhong Cao Yao), a representative journal in CHM. Our study focused on 781 articles in CHM resources from 2013 to 2018 and included four subject areas: germplasm resources, quality analysis and evaluation, cultivation, and bioengineering of CHM. Discussion and prospective for future investigations were also presented, including: construct the core germplasm of medicinal plants and expand germplasms; combine molecular research with field experiments and promote the deeper study of cultivation of CHM plants; improve the quality evaluation method of CHM and strengthen the identification of Chinese patented medicines; promote the sustainable development of CHM resources by utilizing bioengineering and synthetic biology. This study helps international scholars understand the status quo of CHM research and provides theoretical support for the healthy, modern, and international development of CHM, and it will facilitate the sustainable development of the traditional Chinese medicine industry.