Collagen fleece failed to prevent intrapleural adhesions in a canine model: failure of murine models to translate into a large animal model.
Collagen fleece failed to prevent intrapleural adhesions in a canine model: failure of murine models to translate into a large animal model.
复制标题
胶原羊毛未能防止犬模型中的胸膜内粘连：鼠模型未能转化为大型动物模型。
DOI：
10.1007/s11748-013-0369-3
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
T.:
中科院分区：
文献类型：
--
作者：
Hamaji;M.;Kojima;F.;Nakamura;T.:
在临床应用前，在小鼠模型中研究了胸膜内和抗粘连材料，但未在大型动物模型中研究。我们的研究结果未能显示胶原纤维网的任何抗粘连作用，并表明小鼠模型中的胸部生理学不会转化为大型动物模型。
Intrapleural and anti-adhesive materials were investigated in murine models, but not in a large animal model before clinical application. Our results failed to show any anti-adhesion effect of collagen fleece and suggested the thoracic physiology in murine models would not translate into a large animal model.