Employing Contemporary Integrative Interpersonal Theory to Understand Dysfunction in Those at Clinical High Risk for Psychosis.
Employing Contemporary Integrative Interpersonal Theory to Understand Dysfunction in Those at Clinical High Risk for Psychosis.
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DOI：
10.1093/schizbullopen/sgac015
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发表时间：
2022-01
期刊：
影响因子：
--
通讯作者：
Mittal, Vijay A
中科院分区：
文献类型：
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作者：
Williams, Trevor F;Ellman, Lauren M;Schiffman, Jason;Mittal, Vijay A
社会功能差与精神病的发展有关;然而，我们目前对精神病风险人群社会功能的理解受到以下因素的限制：（a）人际行为的概念模型差;（B）依赖于与健康对照组的比较（例如，与临床对照相比）。在这项研究中，我们介绍了当代整合人际理论（CIIT），并使用其人际环（IPC）模型比较人际行为特征的临床高风险（ESTA）的精神病，临床对照组和健康对照组。社区样本（N = 3460）用于获得IPC维度的估计值（即，从属关系和优势），然后在完成诊断访谈的大型子样本（N = 337）中进行比较，其中包括一个独立的组，以及几个控制组，范围为精神病脆弱性和内化障碍的程度。与健康对照组相比，抑郁症患者的低隶属度（d = -1.31），与内化障碍组相比，抑郁症患者的优势度更高（d = 0.64）。阴性症状始终与低从属性和低优势相关，而阳性症状主要与寒冷有关。这些结果将精神病风险中的社会功能与丰富的理论框架联系起来，并提出了一个潜在的独特的人际签名。更广泛地说，这项研究表明，CIIT和IPC可能具有实用性，为精神病风险研究中的诊断和治疗开发提供信息。
Poor social functioning is related to the development of psychosis; however, our current understanding of social functioning in those at-risk for psychosis is limited by (a) poor conceptual models of interpersonal behavior and (b) a reliance on comparisons to healthy controls (e.g., vs. clinical controls). In this study, we introduce Contemporary Integrated Interpersonal Theory (CIIT) and use its Interpersonal Circumplex (IPC) model to compare interpersonal behavior traits in those at clinical high-risk (CHR) for psychosis, clinical controls, and healthy controls. A community sample (N = 3460) was used to derive estimates of IPC dimensions (i.e., affiliation and dominance), which were then compared among a large subsample that completed diagnostic interviews (N = 337), which included a CHR group, as well as several control groups ranging on degree of psychosis vulnerability and internalizing disorders. CHR individuals were distinguished from healthy controls by low affiliation (d = –1.31), and from internalizing disorder groups by higher dominance (d = 0.64). Negative symptoms were consistently associated with low affiliation and low dominance, whereas positive symptoms were related primarily to coldness. These results connect social functioning in psychosis risk to a rich theoretical framework and suggest a potentially distinct interpersonal signature for CHR individuals. More broadly, this study suggests that CIIT and the IPC may have utility for informing diagnostics and treatment development in psychosis risk research.