THE EFFECTS OF FRONTAL AND TEMPORAL-PARIETAL LESIONS ON THE AUDITORY EVOKED-POTENTIAL IN MAN
THE EFFECTS OF FRONTAL AND TEMPORAL-PARIETAL LESIONS ON THE AUDITORY EVOKED-POTENTIAL IN MAN
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DOI：
10.1016/0013-4694(80)90328-4
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发表时间：
1980-01-01
期刊：
影响因子：
--
通讯作者：
NEVILLE, HJ
中科院分区：
文献类型：
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作者：
KNIGHT, RT;HILLYARD, SA;NEVILLE, HJ
将背外侧额叶皮质 (n = 10) 或颞顶叶皮质 (n = 10) 单侧病变患者的长潜伏期听觉诱发电位 (AEP) 特性与一组年龄匹配的正常受试者进行比较。额叶皮质的广泛损伤对 AEP 振幅、头皮难治性分布没有影响。额叶病变后，病变对侧耳朵中出现的音调的 AEP 大于同侧耳朵中出现的音调。单侧颞顶损伤后，所有头皮部位的 N1 分量（98 ms 潜伏期）振幅均显着降低，并且随着 ISI [刺激间间隔]的延长，N1 振幅并未增加。 P2 分量（200 毫秒）显示出与正常受试者相同的振幅和不应特性。讨论了颞上平面后皮质和顶叶相邻皮质在 N1 成分产生中所起的关键作用。
The properties of long-latency auditory evoked potentials (AEP) in patients with unilateral lesions of the dorsolateral frontal cortex (n = 10) or temporal-parietal cortex (n = 10) were compared to those of a group of age-matched normal subjects. Extensive lesions of the frontal cortex had no effect on AEP amplitudes, scalp distributions of refractory properties. Following frontal lesions, AEP were larger to tones presented in the ear contralateral to the lesion than they were for tones presented ipsilaterally. Following unilateral temporal-parietal lesions, the N1 component (98 ms latency) was markedly reduced in amplitude at all scalp sites and no increase in N1 amplitude occurred with lengthening ISI [inter-stimulus interval]. The P2 component (200 ms) showed the same amplitude and refractory properties as in the normal subjects. The critical role played by the cortex of the posterior-superior temporal plane and the adjacent cortex of the parietal lobe in the production of the N1 component is discussed.