A miniature, implantable wireless neural stimulation system
A miniature, implantable wireless neural stimulation system
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微型植入式无线神经刺激系统
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发表时间：
2006
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通讯作者：
Scott K. Arfin
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作者：
Scott K. Arfin
在本论文中，我设计了一个无线神经刺激系统。该系统由一个通过计算机接口控制的外部发射器和一个微型可植入无线接收器和刺激器组成。这种植入物是为斑胸草雀量身定制的，斑胸草雀是一种体重只有12-15克的小鸟，是正在进行的序列生成和学习神经机制研究的一部分。植入物组装在一个微型印刷电路板上，包含一个接收器线圈、电池、电极和一个用于数据解调和神经刺激的定制集成电路。该芯片采用标准的0.5μm CMOS工艺制造，能够在100μA至1mA的16个可选电流水平下向4个可寻址电极位置提供双相电流脉冲。此外，双相脉冲可能是反向的。整个植入物的重量不到1.5克，占地面积小于1.5厘米。像这样的小型神经刺激器也应用于失明、帕金森氏症和瘫痪的神经假体。论文导师：Rahul Sarpeshkar职称：电子工程副教授
In this thesis, I present the design of a wireless neural stimulation system. The system consists of an external transmitter, controllable through a computer interface, and a miniature, implantable wireless receiver and stimulator. The implant is tailored for use in zebra finches – small birds weighing just 12-15g – as part of ongoing research into the neural mechanisms of sequence generation and learning. The implant, assembled on a miniature printed circuit board, contains a receiver coil, battery, electrodes, and a custom integrated circuit for data demodulation and neural stimulation. The chip, fabricated in a standard 0.5μm CMOS process, is capable of delivering biphasic current pulses to 4 addressable electrode sites at 16 selectable current levels ranging from 100μA to 1mA. Additionally, the biphasic pulses may be inverted. The entire implant weighs less than 1.5g and occupies a footprint smaller than 1.5cm. A miniaturized neural stimulator such as this one also has applications in neural prostheses for blindness, Parkinson’s disease, and paralysis. Thesis Supervisor: Rahul Sarpeshkar Title: Associate Professor of Electrical Engineering