PREPARATION AND DETERMINATION OF APPARENT DISSOCIATION CONSTANTS OF SOME ALKYLPHOSPHONIC AND DIALKYLPHOSPHINIC ACIDS
PREPARATION AND DETERMINATION OF APPARENT DISSOCIATION CONSTANTS OF SOME ALKYLPHOSPHONIC AND DIALKYLPHOSPHINIC ACIDS
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DOI：
10.1021/ja01110a024
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发表时间：
1953-01-01
影响因子：
15
通讯作者：
KOSOLAPOFF, GM
中科院分区：
文献类型：
--
作者：
CROFTS, PC;KOSOLAPOFF, GM
制备了具有直链和支链的十种烷基膦酸和六种二烷基次膦酸，并对这些物质的分离和纯化进行了观察。结果表明，高度支化的格氏试剂与磷的反应仅限于双取代反应阶段。的酸的表观解离常数测定电位。烷基中特定碳原子上的甲基数目与pK '的大小近似成线性关系。文献中对未取代的烷基膦酸和二烷基次膦酸的离解常数的测定很少。2-4本研究的目的是研究这些酸的烷基内的变化对这些酸的表观解离常数的影响。
Ten alkylphosphonic and six dialkylphosphinic acids with straight chains and with branched chains were prepared and observations were made relative to the isolation and purification of these substances. It was found that highly branched Grignard reagentsreact with phosphorus trichloride only to the stage of disubstitution. The apparent dissociation constants of the acids were determined potentiometrically. An approximately linear relationship was found between the number of methyl groups attached to a specific carbon in the alkyl group and the magnitude of pK'.Only a few determinations of dissociation con-stants of unsubstituted alkylphosphonic and di-alkylphosphinic acids are recorded in the litera-ture. 2-4 The purpose of the present investigation was the study of the effects ofvariations within the alkyl group of the acids on the apparent dissociation constants of these acids.