[Clinical analysis of cervical metastatis from an unknown primary carcinoma].
[Clinical analysis of cervical metastatis from an unknown primary carcinoma].
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原发灶不明的宫颈癌转移的临床分析[J].
DOI：
10.3950/jibiinkoka.108.996
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
E. Yumoto
中科院分区：
文献类型：
--
作者：
T. Takemura;Norihisa Ogata;E. Yumoto
回顾性分析1997年至2004年19例原发灶不明的颈部淋巴结转移患者（男18例，女1例）的临床观察和治疗结果。从组织病理学类型看，鳞状细胞癌16例，腺癌2例，导管癌1例。从淋巴结转移面积最大的部位来看，转移位于颈上部深部，占84%。 11例（扁桃体3例、鼻咽1例、舌根1例、下咽2例、食管1例、喉1例、胆管1例、乳腺1例）经转移灶治疗后证实存在原发灶。扁桃体切除术和盲活检对5例患者有效。十七名患者接受了颈清扫术治疗。 11 名颈清扫术患者接受了放射治疗。 Kaplan-Meier 法测定的总体 3 年生存率为 62%。 17例转移灶行根治性颈清扫术的3年生存率为66%。原发部位已知和原发部位未知的病例治疗后3年生存率分别为55%和83%。对于局部和颈部控制，放射治疗与根治性颈清扫术被认为比根治性颈清扫术更有效。
From 1997 to 2004, 19 cases-18 men and 1 woman-with cervical lymph node metastasis from an unknown primary carcinoma were retrospectively investigated regarding the clinical observation and the treatment outcome. With respect to the histopathological types, 16 cases had squamous cell carcinoma, 2 cases had adenocarcinoma and 1 case had ductal carcinoma. As for the region of lymph node metastasis with maximum size, metastasis located in the upper deep cervical region arrounted for 84%. The presence of primary lesions was comfirmed in 11 cases (3 tonsil, 1 nasopharynx, 1 base of tongue, 2 hypopharynx, 1 esophagus, 1 larynx, 1 gallduct, 1 mammary gland) after the treatment of their metastatic leisions. Tonsillectomy and Blind biopsy were effective for 5 patients. Seventeen patients were treated with neck dissection. Eleven patients with neck dissection underwent radiotherapy. The overall 3-year survival rate as determined by the Kaplan-Meier method was 62%. The 3-year survival rate of the 17 cases whose metastatic leisions were treated with radical neck dissection was 66%. The 3-year survival rate of cases with known primary sites and cases with unknown primary sites after treatment were 55% and 83%, respectively. Radiotherapy with radical neck dissection was thought more effective than radical neck dissection for local and neck control.