Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure.
Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure.
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DOI：
10.1249/jes.0000000000000303
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发表时间：
2022-10-01
影响因子：
5.7
通讯作者：
Cornwell, William K., III
中科院分区：
文献类型：
--
作者：
Huang, Janice;McDonnell, Barry J.;Lawley, Justin S.;Byrd, Jessica;Stohr, Eric J.;Cornwell, William K., III
关键词：
仅在美国就有大约600万人患有心力衰竭(HF)，在欧洲约有1500万人。左心室辅助装置(LVAD)改善了这些患者的存活率，但功能能力可能并未完全改善。这篇文章检验了一种假说，即接受LVAD支持的患者患有持续性的功能能力下降，并探索了运动耐量异常的机制。由机械循环支持装置支持的心力衰竭患者中限制功能能力和运动耐量的机制概述。
Approximately 6 million individuals suffer from heart failure (HF) in the USA alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD suffer from persistent reductions in functional capacity, and explores mechanisms accounting for abnormalities in exercise tolerance. Overview of mechanisms limiting functional capacity and exercise tolerance among patients with heart failure supported by mechanical circulatory support devices.