Bile ducts as a source of pancreatic β cells
Bile ducts as a source of pancreatic β cells
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DOI：
10.1002/bies.20090
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发表时间：
2004-09-01
期刊：
影响因子：
4
通讯作者：
Tosh, D
中科院分区：
文献类型：
--
作者：
Burke, ZD;Shen, CN;Tosh, D
近年来，已经有许多有据可查的例子证明，一种细胞类型可以转化为另一种。两个这样的例子是在肝脏中出现异位胰腺和在胰腺中形成肝组织。肝脏向胰腺的转化为产生产生胰岛素的β细胞用于治疗性移植到糖尿病患者中提出了有趣的可能性。现在有一个惊人的增加，以不断增长的名单胰腺转换：胰腺组织的形成，在发展中的胆道系统。((1))（C）2004 Wiley Periodicals，Inc.
In recent years, there have been a number of well-documented examples demonstrating that one cell type can be converted to another. Two such examples are the appearance of ectopic pancreas in the liver and formation of hepatic tissue in the pancreas. The conversion of liver to pancreas raises the intriguing possibility of generating insulin-producing beta cells for therapeutic transplantation into diabetics. There is now a striking addition to the growing list of pancreatic conversions: the formation of pancreatic tissue in the developing biliary system.((1)) (C) 2004 Wiley Periodicals, Inc.