Effect of multiple light paths on retinal vessel oximetry.
Effect of multiple light paths on retinal vessel oximetry.
复制标题
多光路对视网膜血管血氧饱和度的影响。
DOI：
10.1364/ao.39.001183
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发表时间：
2000
期刊：
影响因子：
1.9
通讯作者：
L. W. Hillman
中科院分区：
文献类型：
--
作者：
Matthew H. Smith;K. Denninghoff;A. Lompado;L. W. Hillman
文献中报道了非侵入性测量视网膜动脉和静脉中血氧饱和度的技术，但没有一种技术对于临床使用足够准确和可靠。为了满足提高准确性的需要，我们提出了一系列血氧饱和度方程，明确考虑了红细胞后向散射和眼底光横向扩散的影响。该方程是针对扫描光束视网膜血管血氧计的特定几何形状导出的;然而，该结果也应适用于摄影血氧计。我们目前在体外和体内的数据表明这些方程的有效性。
Techniques for noninvasively measuring the oxygen saturation of blood in retinal arteries and veins are reported in the literature, but none have been sufficiently accurate and reliable for clinical use. Addressing the need for increased accuracy, we present a series of oximetric equations that explicitly consider the effects of backscattering by red blood cells and lateral diffusion of light in the ocular fundus. The equations are derived for the specific geometry of a scanning-beam retinal vessel oximeter; however, the results should also be applicable to photographic oximeters. We present in vitro and in vivo data that suggest the validity of these equations.