Antidepressants for the Virtually Eviscerated Patient: Options Instead of Oral Dosing

Antidepressants for the Virtually Eviscerated Patient: Options Instead of Oral Dosing
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用于几乎掏空病人的抗抑郁药:替代口服给药的选择

DOI:
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发表时间:
1998
影响因子:
3.3
通讯作者:
J. Dimsdale
J. Dimsdale
中科院分区:
医学3区
文献类型:
--
作者:
Jonathan S. Koelle;J. Dimsdale

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目的 讨论无法口服抗抑郁药时的替代给药方法。方法 对 1) 妨碍口服药物给药的医疗环境和 2) 抗抑郁药的新给药策略进行了回顾。结果 咨询精神科医生时常会遇到缺乏胃肠道功能、因此无法吸收口服抗抑郁药物的抑郁症患者。在这些情况下,抗抑郁药可以静脉内、直肠栓剂或局部给药。结论 当无法口服抗抑郁药物时,有多种选择。
Objective Alternate ways of administering antidepressants when oral intake is impossible are discussed. Method Reviews of 1) the medical circumstances that preclude oral medication administration and 2) novel administration strategies for antidepressants were conducted. Results Consultation psychiatrists not infrequently encounter depressed patients who lack a functioning gastrointestinal tract and who thus cannot absorb oral antidepressant medication. Under these circumstances, antidepressants can be administered intravenously, by rectal suppository, or topically. Conclusion There are options for administration of antidepressant medication when oral intake is impossible.
DOI: 10.1176/ajp.154.3.396
发表时间: 1997-03
期刊: The American journal of psychiatry
影响因子: --
作者:
L. Koran;F. Sallee;S. Pallanti
通讯作者: L. Koran;F. Sallee;S. Pallanti
静脉注射和口服氯米帕明脉冲负荷后的急性抗抑郁作用。
DOI: 10.1001/archpsyc.1989.01810010031005
发表时间: 1989
影响因子: --
作者:
Pollock,BG;Perel,JM;Nathan,RS;Kupfer,DJ
通讯作者: Kupfer,DJ