Incidence and Risk Factors for Acute Kidney Injury and Its Effect on Mortality in Patients Hospitalized From COVID-19.
Incidence and Risk Factors for Acute Kidney Injury and Its Effect on Mortality in Patients Hospitalized From COVID-19.
复制标题
DOI：
10.1016/j.mayocpiqo.2020.07.003
复制
发表时间：
2020-12-01
期刊：
影响因子：
--
通讯作者：
Jesmajian, Stephen
中科院分区：
文献类型：
--
作者：
Nimkar, Abhishek;Naaraayan, Ashutossh;Jesmajian, Stephen
目的：确定急性肾损伤（阿基）的发生率和风险因素，并研究阿基与2019年因冠状病毒病住院患者死亡率之间的相关性（COVID-19）感染。患者和方法：该回顾性病例系列包括2020年3月10日至5月13日期间因确诊COVID-19疾病连续住院的前370名患者，2020年，在一家拥有242张床位的教学医院。为了确定人口统计学因素、共病情况和阿基发病率之间的独立关联，使用多变量logistic回归模型估计调整临床协变量后的比值比。结果：患者的中位年龄为71岁（四分位距，59-82），44.3%（145/327）为女性。阿基患者年龄明显偏大，共病负担和死亡率较高（58.1% [179例中的104例] vs 19.6% [148例中的29例]; P
OBJECTIVE: To determine the incidence of and risk factors for the development of acute kidney injury (AKI) and investigate the association between AKI and mortality in patients hospitalized with coronavirus disease 2019 (COVID-19) infection.PATIENTS AND METHODS: This retrospective case series includes the first 370 patients consecutively hospitalized with confirmed COVID-19 illness between March 10, 2020, and May 13, 2020, at a 242-bed teaching hospital. To determine independent associations between demographic factors, comorbid conditions, and AKI incidence, multivariable logistic regression models were used to estimate odds ratios adjusted for clinical covariates.RESULTS: Median age of patients was 71 (interquartile range, 59-82) years and 44.3% (145 of 327) were women. Patients with AKI were significantly older with a higher comorbid condition burden and mortality rate (58.1% [104 0f 179] vs 19.6% [29 of 148]; P