Breakthrough pain and its treatment: critical review and recommendations of IOPS (Italian Oncologic Pain Survey) expert group
Breakthrough pain and its treatment: critical review and recommendations of IOPS (Italian Oncologic Pain Survey) expert group
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DOI：
10.1007/s00520-015-2951-y
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发表时间：
2016-02-01
影响因子：
3.1
通讯作者：
Caraceni, Augusto
中科院分区：
文献类型：
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作者：
Mercadante, Sebastiano;Marchetti, Paolo;Caraceni, Augusto
关于突破性癌症疼痛(BTcP)的定义和流行病学，药物治疗的选择，药物剂量，以及如何在新的芬太尼产品中选择治疗BTcP的药物，存在争议。一个专家组对现有数据进行了严格评估，以提供建议。应该使用诊断BTcP的算法，然后进行仔细的评估。芬太尼产品提供了有效和快速的作用，以抵消BTcP的时间模式。用于背景疼痛的阿片类药物的剂量应指导芬太尼产品的剂量选择。芬太尼产品的选择应根据个人的临床情况。
Controversies exist about the definition and epidemiology of breakthrough cancer pain (BTcP), the pharmacological treatment options, drug dosing, and how to select the medications for BTcP among the new fentanyl products. Existing data were critically evaluated to provide recommendations by an expert group. An algorithm to diagnose BTcP should be used followed by a careful assessment. Fentanyl products provide efficacy and rapidity of action to counteract the temporal pattern of BTcP. The doses of opioids used for background pain should guide the choice of the doses of fentanyl products. The choice of fentanyl products should be based on individual clinical conditions.