COVID-19 in long-term care facilities: An upcoming threat that cannot be ignored
COVID-19 in long-term care facilities: An upcoming threat that cannot be ignored
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DOI：
10.1016/j.jmii.2020.04.008
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发表时间：
2020-06-01
影响因子：
7.4
通讯作者：
Hsueh, Po-Ren
中科院分区：
文献类型：
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作者：
Lai, Chih-Cheng;Wang, Jui-Hsiang;Hsueh, Po-Ren
迄今为止，全球共有693，224名患者感染了严重急性呼吸道综合征冠状病毒2（SARS-CoV-2）。1 SARS-CoV-2只花了大约100天就造成了如此广泛的损害。这表明这种感染可以通过人与人之间的接触迅速传播，相关的生殖数量可能很高。2，3根据世界卫生组织（WHO）的每日情况报告，33，106例2019冠状病毒病（COVID-19）感染导致死亡，病死率为4. 78%。1额外的研究表明，很大一部分COVID-19患者有基础疾病或疾病，4，5，6，老年与不良结局显著相关。7，8，9中国和意大利80岁以上的COVID-19患者的病死率分别约为21. 9%和20. 2%，远高于无任何基础合并症的患者。10总体而言，这表明居住在长期护理机构（LTCF）的老年患者可能易受SARS-CoV-2感染，并面临COVID-19相关发病率和死亡率的高风险。
To date, a total of 693,224 patients have been infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide. 1 It only took approximately 100 days for SARS-CoV-2 to cause such extensive damage. This suggests that this infection can be rapidly transmitted by human-to-human contact and the associated reproductive number may be high. 2, 3 According to the daily situation report from the World Health Organization (WHO), 33,106 coronavirus disease 2019 (COVID-19) infections have led to death, corresponding to a fatality rate of 4.78%. 1 Additional studies have demonstrated that a significant portion of COVID-19 patients had underlying conditions or diseases, 4, 5, 6 and old age was significantly associated with poor outcomes. 7, 8, 9 The fatality rates for COVID-19 patients over 80 years old are approximately 21.9% in China and 20.2% in Italy, which are much higher than those of patients without any underlying comorbidity. 10 Overall, this suggests that elderly patients residing in long-term care facilities (LTCFs) could be vulnerable to SARS-CoV-2 infection and at a high risk for COVID-19-associated morbidity and mortality.