Ir-catalyzed functionalization of 2-substituted indoles at the 7-position: Nitrogen-directed aromatic borylation

Ir-catalyzed functionalization of 2-substituted indoles at the 7-position: Nitrogen-directed aromatic borylation
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DOI:
10.1021/ja0631652
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发表时间:
2006-12-13
影响因子:
15
通讯作者:
Smith, Milton R., III
Smith, Milton R., III
中科院分区:
化学1区
文献类型:
--
作者:
Paul, Sulagna;Chotana, Ghayoor A.;Smith, Milton R., III

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ir催化2-取代吲哚的硼化反应选择性地产率高的7-硼化产物。以前2-取代吲哚功能化所需的n保护是不必要的。
Ir-catalyzed borylation of 2-substituted indoles selectively yields 7-borylated products in good yields. N-Protection, required for previous functionalizations of 2-substituted indoles, is unnecessary.