Epidemiology of skin cancer: role of some environmental factors.
Epidemiology of skin cancer: role of some environmental factors.
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DOI：
10.3390/cancers2041980
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发表时间：
2010-11-24
期刊：
影响因子：
5.2
通讯作者：
Monfrecola G
中科院分区：
文献类型：
--
作者：
Fabbrocini G;Triassi M;Mauriello MC;Torre G;Annunziata MC;De Vita V;Pastore F;D'Arco V;Monfrecola G
黑色素瘤和非黑色素瘤皮肤癌实体的发病率在世界范围内急剧增加。众所周知，暴露于UVB辐射会以剂量依赖的方式诱发基底细胞和鳞状细胞皮肤癌，平流层臭氧的消耗会增加到达地球表面的具有生物破坏性的太阳UVB辐射。在人类中，砷已知会导致皮肤癌，以及肺癌，膀胱癌，肝癌和肾癌。在世界一些地区，人们已经认识到饮用水中含有高水平的砷。SCC和BCC（鳞状细胞癌和基底细胞癌）已被报道与单独摄入砷或与其他风险因素结合摄入砷有关。环境温度变化的影响会影响人们的行为和他们在户外度过的时间。伴随气候变化的气温升高可能导致皮肤癌发病率增加，以及许多其他影响。
The incidence rate of melanoma and non-melanoma skin cancer entities is dramatically increasing worldwide. Exposure to UVB radiation is known to induce basal and squamous cell skin cancer in a dose-dependent way and the depletion of stratospheric ozone has implications for increases in biologically damaging solar UVB radiation reaching the earth’s surface. In humans, arsenic is known to cause cancer of the skin, as well as cancer of the lung, bladder, liver, and kidney. Exposure to high levels of arsenic in drinking water has been recognized in some regions of the world. SCC and BCC (squamous and basal cell carcinoma) have been reported to be associated with ingestion of arsenic alone or in combination with other risk factors. The impact of changes in ambient temperature will influence people’s behavior and the time they spend outdoors. Higher temperatures accompanying climate change may lead, among many other effects, to increasing incidence of skin cancer.