Corneal electrolysis for recurrence of corneal stromal dystrophy after keratoplasty

Corneal electrolysis for recurrence of corneal stromal dystrophy after keratoplasty
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DOI:
10.1136/bjo.86.3.273
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发表时间:
2002-03-01
影响因子:
4.1
通讯作者:
Yamada, M
Yamada, M
中科院分区:
医学2区
文献类型:
--
作者:
Mashima, Y;Kawai, M;Yamada, M

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目的:评估角膜电解作为治疗复发性弥漫性角膜混浊在宿主-移植物界面的基质或在上皮下区域在两种类型的颗粒状角膜营养不良(GCD)。方法:复发开发的板层角膜移植术后的基质的宿主-移植物界面的患者Avellino角膜营养不良(ACD)。在手术中,该患者的移植物深部部分与宿主组织分离,暴露沉积物,宿主-移植物连接处的三分之一完好无损。将移植物外翻,并直接电解以去除附着在宿主和移植物两个表面的沉积物。然后将其放回原位并缝合。在两名纯合子ACD患者和一名GCD浅表变异患者中,穿透性角膜移植术后出现弥漫性上皮下混浊。电解直接应用于角膜surfaces.Results:在基质和上皮下区域的宿主-移植物界面的沉积物消失后的治疗,视力恢复在所有patients.Conclusions:这种方法是一种简单,容易,廉价的方式来去除沉积物,板层或穿透性角膜移植术后复发。
Aims: To evaluate corneal electrolysis as a treatment for recurrent diffuse corneal opacities at the host-graft interface of the stroma or at the subepithelial region in two types of granular corneal dystrophy (GCD).Methods: Recurrence developed at the host-graft interface of the stroma after lamellar keratoplasty in a patient with Avellino corneal dystrophy (ACD). At surgery,,the deep aspect of the graft in this patient was partially separated from host tissue to expose the deposits, with one third of the host-graft junction left intact. The graft was everted, and electrolysis was applied directly to remove the deposits attached to both surfaces of the host and the graft. Then the Waft was returned to its place and sutured. In two patients with homozygous ACD and one patient with the superficial variant of GCD, diffuse subepithelial opacities developed following penetrating keratoplasty. Electrolysis was applied directly to the corneal surface.Results: Deposits at the host-graft interface of the stroma and in the subepithelial region disappeared following treatment, and vision recovered in all patients.Conclusions: This method is a simple, easy, and inexpensive way to remove deposits that recur after lamellar or penetrating keratoplasty.