Age and Pattern of Pap Smear Abnormalities: Implications for Cervical Cancer Control in a Developing Country.
Age and Pattern of Pap Smear Abnormalities: Implications for Cervical Cancer Control in a Developing Country.
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DOI：
10.4103/joc.joc_199_15
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发表时间：
2017-10
影响因子：
1.3
通讯作者：
Onwundiegu U
中科院分区：
文献类型：
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作者：
Akinfolarin AC;Olusegun AK;Omoladun O;Omoniyi-Esan GO;Onwundiegu U
描述尼日利亚西南部一家主要教学医院子宫颈抹片检查异常的年龄和模式。这是对前来接受宫颈癌筛查的患者病历的回顾。检索2013年5月至2015年4月期间女性子宫颈抹片检查结果。研究期间共检索了 2048 份子宫颈抹片结果，并使用社会科学统计软件包 (SPSS) 20 版进行分析。总共有 252 个 (12.3%) 样本被排除在分析之外。女性的平均年龄为 45.77 ± 9.9 岁，众数为 50 岁。 728 名 (40.6%) 女性的子宫颈抹片检查结果正常。只有 20 名女性做过不止一次子宫颈抹片检查。最常见的异常是炎症涂片结果，有 613 名 (29.9%) 女性报告有此结果。意义不明的非典型鳞状细胞、低度鳞状上皮内病变 (LGSIL) 和高度鳞状上皮内病变 (HGSIL) 分别报告于 117 名 (5.7%)、209 名 (10.2%) 和 111 名 (5.4%) 女性。据报道，非典型腺细胞癌和鳞状细胞癌分别为 12 例（6.0%）和 3 例（1.0%）。在这种环境下，子宫颈抹片检查异常的发生率很高，并且女性在生育年龄较晚时开始宫颈癌筛查，超过了宫颈癌前病变的高峰年龄。这可能是发展中国家宫颈癌负担较高的一个因素。
To characterize the age and pattern of Pap smear abnormalities in a major teaching hospital in Southwestern Nigeria. This is a review of medical records of patients that came for cervical cancer screening. The Pap smear results of women between May 2013 and April 2015 were retrieved. A total of 2048 Pap smear results were retrieved during the study period and analyzed with Statistical Package for Social Sciences (SPSS) version 20. A total of 252 (12.3%) samples were excluded from the analysis. The mean age of the women was 45.77 ± 9.9 years and the mode was 50 years. Normal Pap smear result was reported in 728 (40.6%) women. Only 20 women has had more than one more than one Pap smear done. The most common abnormality was inflammatory smear result as this was reported in 613 (29.9%) women. Atypical squamous cell of undetermined significance, low-grade squamous intraepithelial lesion (LGSIL), and high-grade squamous intraepithelial lesion (HGSIL) were reported in 117 (5.7%), 209 (10.2%), and 111 (5.4%) women, respectively. Atypical glandular cell and squamous cell carcinoma were reported in 12 (6.0%) and 3 (1.0%), respectively. There is a high incidence of abnormal Pap smear in this environment and women start cervical cancer screening late in their reproductive life, past the age at which cervical premalignant lesions peak. This may be a contributing factor to the high burden of cervical cancer in developing countries.