Yellow fever: a reemerging threat.

Yellow fever: a reemerging threat.
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DOI:
10.1016/j.cll.2010.01.001
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发表时间:
2010-03
影响因子:
1.7
通讯作者:
Ryman KD
Ryman KD
中科院分区:
医学4区
文献类型:
--
作者:
Gardner CL;Ryman KD

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黄热病(YF)是一种病毒性疾病,流行于非洲和美洲的热带地区。YF主要影响人类和非人灵长类动物,并通过受感染的蚊子叮咬传播。黄热病病毒(YFV)是黄热病的病原体,可引起潜在致命的出血性疾病的毁灭性流行。我们依靠大规模疫苗接种运动来预防和控制这些疫情。然而,主要的YF流行病的风险,特别是在非洲和南美洲人口稠密的贫困城市环境中,由于以下原因而大大增加:(1)YF蚊子媒介埃及伊蚊再次入侵城市环境;(2)快速城市化,特别是在非洲部分地区,人口从农村转移到主要的城市;以及(3)免疫覆盖率下降。因此,YF被认为是一种相当重要的新出现或重新出现的疾病。
Yellow fever (YF) is a viral disease, endemic to tropical regions of Africa and the Americas. YF principally affects humans and nonhuman primates, and is transmitted via the bite of infected mosquitoes. The agent of YF, yellow fever virus (YFV), can cause devastating epidemics of potentially fatal, hemorrhagic disease. We rely on mass vaccination campaigns to prevent and control these outbreaks. However, the risk of major YF epidemics, especially in densely populated, poor urban settings, both in Africa and South America, has greatly increased due to: (1) reinvasion of urban settings by the mosquito vector of YF, Aedes aegypti; (2) rapid urbanization, particularly in parts of Africa, with populations shifting from rural to predominantly urban; and (3) waning immunization coverage. Consequently, YF is considered an emerging, or reemerging disease of considerable importance.
DOI: 10.1006/viro.1993.1198
发表时间: 1993-04-01
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