Automated molecular microscopy: The new Leginon system
Automated molecular microscopy: The new Leginon system
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DOI：
10.1016/j.jsb.2005.03.010
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发表时间：
2005-07-01
影响因子：
3
通讯作者：
Carragher, B
中科院分区：
文献类型：
--
作者：
Suloway, C;Pulokas, J;Carragher, B
我们在这里报告我们在自动分子显微镜方面的努力的现状。我们的主要自动化数据采集软件系统Leginon在过去两年中进行了彻底的重新设计。新的分布式系统使用Python编程语言开发，兼容Linux和Windows操作系统。新的灵活架构旨在允许开发自定义数据收集协议，这里将介绍其中的几个协议。该系统已被用于获取类似150个实验的数据，我们已经证明了在显微镜下单次获取超过100,000个粒子的图像的高通量数据采集能力。(C) 2005爱思唯尔公司版权所有。
We report here on the current state of our efforts in automated molecular microscopy. Our primary automated data acquisition software system, Leginon, has been completely redesigned over the past two years. The new distributed system has been developed using the Python programming language and is compatible with both Linux and Windows operating systems. The new flexible architecture was designed to allow for the development Of Customized data collection protocols, several of which are described here. The system has been used to acquire data for similar to 150 experiments and we have demonstrated the capacity for high throughput data acquisition by acquiring images of more than 100 000 particles in a single session at the microscope. (C) 2005 Elsevier Inc. All rights reserved.