An analysis of challenging behavior, comorbid psychopathology, and Attention-Deficit/Hyperactivity Disorder in Fragile X Syndrome
An analysis of challenging behavior, comorbid psychopathology, and Attention-Deficit/Hyperactivity Disorder in Fragile X Syndrome
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DOI：
10.1016/j.ridd.2014.11.003
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发表时间：
2015-03-01
影响因子：
3.1
通讯作者：
Mannion, Arlene
中科院分区：
文献类型：
--
作者：
Newman, Isabel;Leader, Geraldine;Mannion, Arlene
本研究旨在探讨脆性X综合征（FRAX）患者的挑战行为、共病精神病理学和注意力缺陷/多动障碍（AD/HD）之间的关系。此外，这项研究试图研究如何通过性别，自闭症谱系障碍（ASD）的存在和智力残疾（ID）的存在来预测这些疾病。共对47名患有FRAX的儿童和青少年进行了评估。结果显示，样本中存在高水平的挑战行为和AD/HD症状，一些参与者表现出共病精神病理学症状。进一步的分析显示，挑战行为和共病的精神病理学呈正相关，刻板印象与共病的精神病理学相关性最强。此外，ASD被发现预测挑战行为，性别被发现预测AD/HD症状。这些研究结果的影响进行了讨论。(C)2014爱思唯尔有限公司版权所有。
The present study sought to investigate the relationship between challenging behavior, comorbid psychopathology, and Attention-Deficit/Hyperactivity Disorder (AD/HD) in Fragile X Syndrome (FRAX). Additionally, this study sought to examine how such disorders are predicted by gender, presence of autism spectrum disorder (ASD), and presence of intellectual disability (ID). A total of 47 children and adolescents with FRAX were assessed. Results revealed high levels of challenging behavior and AD/HD symptoms within the sample, with some participants exhibiting symptoms of comorbid psychopathology. Further analysis revealed that challenging behavior and comorbid psychopathology were positively correlated, with stereotypy correlating most strongly with comorbid psychopathology. In addition, ASD was found to predict challenging behavior, and gender was found to predict AD/HD symptoms. The implications of these findings are discussed. (C) 2014 Elsevier Ltd. All rights reserved.