Rapid Enzyme-linked Immunosorbent Assays for Diagnosis of Diabetes in a Compact Disc-shaped Microfluidic Device

Rapid Enzyme-linked Immunosorbent Assays for Diagnosis of Diabetes in a Compact Disc-shaped Microfluidic Device
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DOI:
10.2116/analsci.34.379
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发表时间:
2018-03-01
影响因子:
1.6
通讯作者:
Nagai, Hidenori
Nagai, Hidenori
中科院分区:
化学4区
文献类型:
--
作者:
Furutani, Shunsuke;Nishio, Keiko;Nagai, Hidenori

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我们已经开发了一个光盘(CD)形状的微流控装置,用于多个,快速酶联免疫吸附测定(ELISA)。该设备具有通用设计,通过为每个目标选择推入式反应部件和适当的试剂,可适用于检测各种蛋白质。在本文中,我们报告的快速定量胰岛素,脂联素,瘦素,可用于糖尿病的早期诊断,在人血清中,只有16分钟,我们的设备。
We have developed a compact disc (CD)-shaped microfluidic device for multiple, rapid enzyme-linked immunosorbent assays (ELISA). The device has a versatile design that can be adapted for the detection of various proteins by selecting the push-in-type reaction parts and appropriate reagents for each target. In this paper, we report the rapid quantification of insulin, adiponectin, and leptin, which can be used for the early diagnosis of diabetes, in human serum in only 16 min with our device.