The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ)
The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ)
复制标题
DOI：
10.1128/jb.184.19.5513-5517.2002
复制
发表时间：
2002-10-01
影响因子：
3.2
通讯作者：
Masters, M
中科院分区：
文献类型：
--
作者：
Merlin, C;Gardiner, G;Masters, M
我们报告的基因abc，yaeC，和yaeE包括metD，大肠杆菌基因座编码DL-甲硫氨酸摄取系统。MetD是ABC转运蛋白，其中Abc是ATP酶，YaeE是通透酶，YaeC是可能的底物结合蛋白。这些基因的表达受L-甲硫氨酸和MetJ（甲硫氨酸调节子的共同阻遏物）的调控。我们建议将abc、yaeE和yaeC分别重命名为metN、metI和metQ。
We report that the genes abc, yaeC, and yaeE comprise metD, an Escherichia coli locus encoding a DL-methionine uptake system. MetD is an ABC transporter with Abc the ATPase, YaeE the permease, and YaeC the likely substrate binding protein. Expression of these genes is regulated by L-methionine and MetJ, a common repressor of the methionine regulon. We propose to rename abc, yaeE, and yaeC as metN, metI, and metQ, respectively.