Influence of periodontal afferent inputs for human cerebral blood oxygenation during jaw movements
Influence of periodontal afferent inputs for human cerebral blood oxygenation during jaw movements
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DOI：
10.1007/s00221-011-2941-3
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发表时间：
2012-02-01
影响因子：
2
通讯作者：
Kawara, Misao
中科院分区：
文献类型：
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作者：
Iida, Takashi;Sakayanagi, Masashi;Kawara, Misao
利用功能磁共振成像（fMRI）和近红外光谱（NIRS），我们研究了22名受试者的牙周传入输入的咀嚼肌活动引起的脑激活模式的作用。在fMRI（N = 14）和NIRS研究（N = 8）中，使用统计学比较来识别从假叩齿（无牙周输入）和叩齿（牙周输入）活动中减去基线活动后具有显著激活的脑区。在fMRI研究中，假叩齿和叩齿都显著激活了双侧感觉运动皮层和辅助运动区。近红外光谱显示，氧合血红蛋白浓度增加的感觉运动皮层，但是，有没有显着差异的氧合血红蛋白的变化程度之间的假叩齿和叩齿。一项对照研究（N = 8）的特点是下颌肌肉活动和幅度的两个运动任务，并表现出显着更高的肌电图（EMG）活动在下颌闭合肌肉在牙齿接触的牙齿敲击会话。由于大脑激活在假牙齿敲击和牙齿敲击是相似的，我们认为，牙周传入输入和相关的下颌肌肉活动的影响是相对较小的节奏相比，下颌运动。虽然目前的研究结果的临床意义仍然是未知的，他们可能有意义的理解清醒或睡眠相关的磨牙症的特点是潜意识和有节奏的磨牙或咬牙。
Using functional magnetic resonance imaging (fMRI) and near-infrared spectroscopy (NIRS), we examined the role of periodontal afferent inputs on cerebral activation pattern evoked by masticatory muscle activity in twenty-two subjects. Statistical comparisons were used to identify brain regions with significant activation after subtraction of baseline activity from sham teeth-tapping (no periodontal input) and teeth-tapping (periodontal input) activity in an fMRI (N = 14) and NIRS study (N = 8). Both sham teeth-tapping and teeth-tapping significantly activated bilateral sensorimotor cortex and supplementary motor area in the fMRI study. NIRS revealed that oxygenated hemoglobin concentrations increased in sensorimotor cortex; however, there was no significant difference in degree of oxygenated hemoglobin changes between sham teeth-tapping and teeth-tapping. A control study (N = 8) characterized the jaw muscle activity and amplitude of the two motor tasks and demonstrated significantly higher electromyogram (EMG) activity in the jaw closing muscles during teeth contact in the teeth-tapping session. Since the cerebral activation during sham teeth-tapping and teeth-tapping was similar, we suggest that the influence of periodontal afferent inputs and associated jaw muscle activity is relatively minor compared to the rhythmic jaw movements. Although the clinical significance of the present findings remains unknown, they may have implications for the understanding of awake or sleep-related bruxism characterized by subconscious and rhythmic teeth-grinding or teeth-clenching.