DRUG-RESISTANT SALMONELLA IN THE UNITED-STATES - AN EPIDEMIOLOGIC PERSPECTIVE

DRUG-RESISTANT SALMONELLA IN THE UNITED-STATES - AN EPIDEMIOLOGIC PERSPECTIVE
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DOI:
10.1126/science.3535069
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发表时间:
1986-11-21
期刊:
影响因子:
56.9
通讯作者:
TAUXE, RV
TAUXE, RV
中科院分区:
综合性期刊1区
文献类型:
--
作者:
COHEN, ML;TAUXE, RV

文献摘要

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Salmonellosis poses a health problem of large proportions in the United States. Annually, it accounts for more than 40,000 reported cases, 500 deaths, and financial costs well in excess of $50 million. Antimicrobial resistance is increasing inSalmonellastrains, a finding that has important public health implications. Although the chain of transmission of the bacteria is often complex, combined epidemiologic and laboratory studies with the use of new methods in molecular biology make it possible to trace antimicrobial-resistant salmonellae to their primary source—foods of animal origin. These studies suggest that the antimicrobial drugs to which food animals are exposed provide selective pressure that leads to the appearance and persistence of resistant strains.