Report of incidence and mortality in China cancer registries, 2009
Report of incidence and mortality in China cancer registries, 2009
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DOI：
10.3978/j.issn.1000-9604.2012.12.04
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发表时间：
2013-02-01
影响因子：
5.1
通讯作者：
He, Jie
中科院分区：
文献类型：
--
作者：
Chen, Wanqing;Zheng, Rongshou;He, Jie
目的：方法：根据全国肿瘤登记中心（NCCR）的数据质量标准，对104个肿瘤登记中心2009年和2012年的数据进行分析。2012年，有72个登记中心的数据合格并被接受用于癌症登记中心年度报告。描述性分析包括按地区（城市/农村）、性别、年龄组和癌症部位分层的发病率和死亡率。统计各组前10位的常见癌、比例及累积发病率。结果：72个肿瘤登记点共覆盖85，470，522人，其中城市57，489，009人，农村27，981，513人。新增癌症病例和癌症死亡总数分别为244，366和154，310。形态学证实的病例占67.23%，仅死亡证明信息的病例占3.14%。中国肿瘤登记地区粗发病率为285.91/10万（男性317.97/10万，女性253.09/10万），中国标准人群（ASIRC）和世界标准人群（ASIRW）年龄标化发病率分别为146.87/10万和191.72/10万，累计发病率（0-74岁）为22.08%。城市地区恶性肿瘤发病率和ASIRC分别为303.39/10万和150.31/10万，农村地区分别为249.98/10万和139.68/10万。中国恶性肿瘤登记地区恶性肿瘤死亡率为180.54/10万（男性224.20/10万，女性135.85/10万），中国标准人群和世界标准人群年龄标化死亡率分别为85.06/10万和115.65/10万，累计发病率（0-74岁）为12.94%。城市恶性肿瘤死亡率和ASMRC分别为181.86/10万和80.86/10万，农村分别为177.83/10万和94.40/10万。肺癌、胃癌、结直肠癌、肝癌、食管癌、胰腺癌、脑瘤、淋巴瘤、女性乳腺癌和宫颈癌是最常见的癌症，占城市和农村地区所有癌症病例的75%。肺癌、胃癌、肝癌、食管癌、结直肠癌、胰腺癌、乳腺癌、脑瘤、白血病和淋巴瘤占所有癌症死亡的80%。癌症谱存在城乡、男女差异。农村地区主要恶性肿瘤为胃癌，其次为食管癌、肺癌、肝癌和结直肠癌;城市地区主要恶性肿瘤为肺癌，其次为肝癌、胃癌和结直肠癌。肿瘤登记作为肿瘤控制计划的基础，对制定中长期抗癌策略具有重要作用。由于我国癌症负担存在城乡差异，应根据实际情况实施预防和控制。
Objective: The National Central Cancer Registry (NCCR) collected cancer registration data in 2009 from local cancer registries in 2012, and analyzed to describe cancer incidence and mortality in China.Methods: On basis of the criteria of data quality from NCCR, data submitted from 104 registries were checked and evaluated. There were 72 registries' data qualified and accepted for cancer registry annual report in 2012. Descriptive analysis included incidence and mortality stratified by area (urban/rural), sex, age group and cancer site. The top 10 common cancers in different groups, proportion and cumulative rates were also calculated. Chinese population census in 1982 and Segi's population were used for age-standardized incidence/mortality rates.Results: All 72 cancer registries covered a total of 85,470,522 population (57,489,009 in urban and 27,981,513 in rural areas). The total new cancer incident cases and cancer deaths were 244,366 and 154,310, respectively. The morphology verified cases accounted for 67.23%, and 3.14% of incident cases only had information from death certifications. The crude incidence rate in Chinese cancer registration areas was 285.91/100,000 (males 317.97/100,000, females 253.09/100,000), age-standardized incidence rates by Chinese standard population (ASIRC) and by world standard population (ASIRW) were 146.87/100,000 and 191.72/100,000 with the cumulative incidence rate (0-74 age years old) of 22.08%. The cancer incidence and ASIRC were 303.39/100,000 and 150.31/100,000 in urban areas whereas in rural areas, they were 249.98/100,000 and 139.68/100,000, respectively. The cancer mortality in Chinese cancer registration areas was 180.54/100,000 (224.20/100,000 in males and 135.85/100,000 in females), age-standardized mortality rates by Chinese standard population (ASMRC) and by world standard population (ASMRW) were 85.06/100,000 and 115.65/100,000, and the cumulative incidence rate (0-74 age years old) was 12.94%. The cancer mortality and ASMRC were 181.86/100,000 and 80.86/100,000 in urban areas, whereas in rural areas, they were 177.83/100,000 and 94.40/100,000 respectively. Lung cancer, gastric cancer, colorectal cancer, liver cancer, esophageal cancer, pancreas cancer, encephaloma, lymphoma, female breast cancer and cervical cancer, were the most common cancers, accounting for 75% of all cancer cases in urban and rural areas. Lung cancer, gastric cancer, liver cancer, esophageal cancer, colorectal cancer, pancreatic cancer, breast cancer, encephaloma, leukemia and lymphoma accounted for 80% of all cancer deaths. The cancer spectrum showed difference between urban and rural areas, males and females. The main cancers in rural areas were cancers of the stomach, followed by esophageal cancer, lung cancer, liver cancer and colorectal cancer, whereas the main cancer in urban areas was lung cancer, followed by liver cancer, gastric cancer and colorectal cancer.Conclusions: The coverage of cancer registration population has been increasing and data quality is improving. As the basis of cancer control program, cancer registry plays an important role in making anticancer strategy in medium and long term. As cancer burdens are different between urban and rural areas in China, prevention and control should be implemented based on practical situation.