Acoel flatworms are not platyhelminthes: evidence from phylogenomics.

Acoel flatworms are not platyhelminthes: evidence from phylogenomics.
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Acoel Flatems不是PlatyHelminthes:系统基因组学的证据。

DOI:
10.1371/journal.pone.0000717
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发表时间:
2007-08-08
期刊:
影响因子:
3.7
通讯作者:
Baguna, Jaume
Baguna, Jaume
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Philippe, Herve;Brinkmann, Henner;Martinez, Pedro;Riutort, Marta;Baguna, Jaume

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扁虫是一种小型的海洋蠕虫,传统上被认为属于扁形动物门。然而,分子系统发育分析表明,acoels不是扁形动物的成员,而是现存的最早的分歧Bilateria的成员。这一结果受到质疑,怀疑是长分支吸引(LBA)假象。在这里,我们重新审视这个问题,通过一个基因组学的方法,使用68个不同的蛋白质编码基因的acoel旋毛虫pulchra和51后生动物物种属于15个不同的门。我们采用了一种混合模型,名为CAT,以前发现克服LBA文物经典模型失败。我们的研究结果明确表明,acoels不是经典定义的扁形动物的一部分,使后者多系。此外,它们表明后口动物的亲和力acoels,潜在的姐妹群,所有后口动物,Xenoturbellida,Ambulacraria,甚至脊索动物。然而,弱支持大多数后口类节点,以及非常快的进化速度的acoel旋花pulchra,要求更多的数据从缓慢发展的acoels(或从它的姐妹组,纽皮动物),以解决这个具有挑战性的系统发育问题。
Acoel flatworms are small marine worms traditionally considered to belong to the phylum Platyhelminthes. However, molecular phylogenetic analyses suggest that acoels are not members of Platyhelminthes, but are rather extant members of the earliest diverging Bilateria. This result has been called into question, under suspicions of a long branch attraction (LBA) artefact. Here we re-examine this problem through a phylogenomic approach using 68 different protein-coding genes from the acoel Convoluta pulchra and 51 metazoan species belonging to 15 different phyla. We employ a mixture model, named CAT, previously found to overcome LBA artefacts where classical models fail. Our results unequivocally show that acoels are not part of the classically defined Platyhelminthes, making the latter polyphyletic. Moreover, they indicate a deuterostome affinity for acoels, potentially as a sister group to all deuterostomes, to Xenoturbellida, to Ambulacraria, or even to chordates. However, the weak support found for most deuterostome nodes, together with the very fast evolutionary rate of the acoel Convoluta pulchra, call for more data from slowly evolving acoels (or from its sister-group, the Nemertodermatida) to solve this challenging phylogenetic problem.
DOI: 10.1093/oxfordjournals.molbev.a026334
发表时间: 2000-04-01
影响因子: 10.7
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DOI: 10.1046/j.1463-6409.2002.00090.x
发表时间: 2002-04-01
期刊: ZOOLOGICA SCRIPTA
影响因子: 2.5
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发表时间: 2006-02-23
期刊: NATURE
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