The Impact of Mild Cognitive Impairment on Decision Making in Two Gambling Tasks
The Impact of Mild Cognitive Impairment on Decision Making in Two Gambling Tasks
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DOI：
10.1093/geronb/gbq067
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发表时间：
2011-01-01
影响因子：
6.2
通讯作者：
Delazer, Margarete
中科院分区：
文献类型：
--
作者：
Zamarian, Laura;Weiss, Elisabeth M.;Delazer, Margarete
目标。本研究旨在探讨轻度认知障碍（MCI）患者在模棱两可和风险下是否存在决策困难。将MCI患者在爱荷华赌博任务（IGT）和概率相关赌博任务修正（PAG-R）中的表现与健康老年同伴进行比较。在IGT中，随着时间的推移，控制组做出越来越频繁的有利选择；MCI患者随机从有利组和不利组中选择，随着时间的推移，他们的表现没有显著变化。在PAG-R中，控制组在两种获胜概率（高、低）的情况下都做出了有利的决定；在低获胜概率的情况下，患者比对照组做出更少的有利决定。在模糊任务下的决策（IGT）中，MCI患者在从反馈中学习和长期保持优势策略方面存在困难。在风险决策任务（PAG-R）中，患者在整合不同来源的信息和适应决策情况变化的策略方面存在问题。综上所述，轻度认知障碍患者在有利决策方面存在困难，类似于那些报道的或轻度痴呆患者。
Objectives. This study aimed to investigate whether patients with mild cognitive impairment (MCI) present difficulties in making decisions under ambiguity and under risk.Methods. Performance of MCI patients in the Iowa Gambling Task (IGT) and in the Probability-Associated Gambling Task-Revised (PAG-R) was compared with performance of healthy aging peers.Results. In the IGT, controls made increasingly frequent advantageous selections over time; MCI patients selected randomly from advantageous and disadvantageous decks, with no significant change in performance over time. In the PAG-R, controls decided advantageously in conditions of both (low, high) winning probabilities; patients made less advantageous decisions than controls in conditions of low winning probability.Discussion. In the decision under ambiguity task (IGT), MCI patients experienced difficulties in learning from feedback and in maintaining an advantageous strategy over time. In the decision under risk task (PAG-R), patients had problems in integrating information from different sources and in adapting their strategy to changes in the decision situation. In summary, MCI patients present difficulties in advantageous decision making that resemble those reported or patients with mild dementia.