EARLY EDUCATIONAL INTERVENTION FOR VERY-LOW-BIRTH-WEIGHT INFANTS - RESULTS FROM THE INFANT-HEALTH-AND-DEVELOPMENT-PROGRAM

EARLY EDUCATIONAL INTERVENTION FOR VERY-LOW-BIRTH-WEIGHT INFANTS - RESULTS FROM THE INFANT-HEALTH-AND-DEVELOPMENT-PROGRAM
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DOI:
10.1016/s0022-3476(05)80945-x
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发表时间:
1993-10-01
影响因子:
5.1
通讯作者:
BROOKSGUNN, J
BROOKSGUNN, J
中科院分区:
医学2区
文献类型:
--
作者:
MCCORMICK, MC;MCCARTON, C;BROOKSGUNN, J

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目的:探讨出院后早期教育干预对极低出生体重儿(小于或等于1500克)健康和发育状况的影响。设计:随机对照试验,后组分析。设置:8个地点,用于社会人口学和医疗保健。参与者:出生体重小于或等于1500克的婴儿(N=280),纳入婴儿健康与发展计划。资格主要受到距离日托中心的地理距离的限制。三分之一的儿童被随机分配到干预组(INT),三分之二的儿童只接受随访。干预:所有儿童都接受了密集的儿科和发育监测。INT组接受家庭访问和以中心为基础的教育干预,直到36个月大(当最终评估完成时,根据胎龄进行校正)。结果:认知发展(斯坦福-比奈智力量表)、行为能力(阿切巴赫儿童行为检查表)和健康状况(概述报告发病率的指数、功能状态II(R)量表和一般健康评级指数)。结果:在调整了地点、社会人口学特征和新生儿发病率的基线差异后,INT组的认知发展得分高出7.2点(p=0.002),并高出9.4点(p
Objective: To examine the effect of early educational intervention after discharge from the hospital on the health and developmental status of very low birth weight (less-than-or-equal-to 1500 gm) infants.Design: Randomized, controlled trial, with post hoc analysis.Setting: Eight sites, heterogeneous for sociodemographic and health care use.Participants: Infants (N = 280) born weighing less-than-or-equal-to 1500 gm and selected for the Infant Health and Development Program. Eligibility was limited primarily by geographic distance from the day care center. One third were randomly assigned to the intervention (INT) group and two thirds to follow-up only.Interventions: All children received intensive pediatric and developmental surveillance. The INT group received home visits and center-based educational interventions until 36 months of age (corrected for gestational age when final assessments were completed).Outcomes: Cognitive development (Stanford-Binet Intelligence Scale), behavioral competence (Achebach Child Behavior Checklist), and health status (indexes summarizing reported morbidity, the Functional Status II (R) Scale, and General Health Ratings Index).Results: Cognitive development scores were 7.2 points higher (p = 0.002) in the INT group, after adjustment for baseline differences in site, sociodemographic characteristics, and neonatal morbidity, and were 9.4 points higher (p