GROWTH REBOUND AFTER TERMINATION OF STIMULANT-DRUGS

GROWTH REBOUND AFTER TERMINATION OF STIMULANT-DRUGS
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DOI:
10.1016/s0022-3476(75)80720-7
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发表时间:
1975-01-01
影响因子:
5.1
通讯作者:
BARR, E
BARR, E
中科院分区:
医学2区
文献类型:
--
作者:
SAFER, DJ;ALLEN, RP;BARR, E

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为了进一步探讨终止兴奋剂治疗后体重增加加速的报道,从1970年至1973年,对66名接受药物治疗的多动学龄儿童进行了两年一次的生长测量。所有人都在学年期间接受了安非他明或哌醋甲酯;有些人还在夏天接受了它。数据显示,那些在夏季开始时停止服用兴奋剂药物的人,其体重和身高的增长速度明显高于那些在6月至9月期间继续接受药物治疗的人。事实上,停药导致这一时期的生长反弹,比年龄预期增量高出15-68%。
To explore further the report1of an accelerated weight gain following termination of treatment with a stimulant drug, 66 biannual growth measurements were obtained from 1970 to 1973 on hyperactive schoolchildren who were receiving medication. All received either dextroamphetamine or methylphenidate during the school year; some also received it during the summer. The data revealed that those whose stimulant medication was terminated at the start of summer subsequently grew in weight and height at a significantly greater rate than those who continued to receive medication from June to September. In fact, discontinuance of the medication resulted in a growth rebound for this period which was 15–68% above the age-expected increment.