Processible polyaniline as an advanced potentiometric pH transducer. Application to biosensors.
Processible polyaniline as an advanced potentiometric pH transducer. Application to biosensors.
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DOI：
10.1021/ac981337a
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发表时间：
1999-05
影响因子：
7.4
通讯作者：
A. Karyakin;M. Vuki;L. V. Lukachova;E. E. Karyakina-E.;A. Orlov;G. P. Karpachova;J. Wang
中科院分区：
文献类型：
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作者：
A. Karyakin;M. Vuki;L. V. Lukachova;E. E. Karyakina-E.;A. Orlov;G. P. Karpachova;J. Wang
报道了一种基于可加工聚苯胺（PCPAn）的新型电位型pH传感器，在pH 3 ~ 9的范围内，PCPAn修饰的玻碳电极和丝网印刷碳电极均表现出约90 mV/pH单位的完全可逆电位响应。这样一个显着更高的电位响应的PCPAn-修饰电极相比，现有的设备解释聚苯胺氧化还原反应的热力学的基础上。基于PCPAn的pH传感器表现出良好的操作稳定性和延长的保质期，并显示对单电荷阳离子的响应可以忽略不计。将这种新型厚膜pH传感器用于尿素电位型生物传感器的设计。在模拟血清的模型溶液中，尿素敏感电极的检测限为10（-5）M尿素，最大响应约为120 mV。有吸引力的性能特点是优于现有的pH传感器，并提供传感和生物传感应用的巨大希望。
An advanced potentiometric pH transducer based on processible polyaniline (PCPAn) is reported on. Both glassy carbon and screen-printed carbon electrodes modified with PCPAn by dip-coating exhibited a fully reversible potentiometric response of approximately 90 mV/pH unit over the range from pH 3 to 9. Such a significantly higher potentiometric response of PCPAn-modified electrodes as compared with those of existing devices is explained on the basis of the thermodynamics of polyaniline redox reactions. The PCPAn-based pH transducers exhibit both good operational stability and prolonged shelf life and display a negligible response toward singly charged cations. The new thick-film pH transducer was employed for designing a potentiometric biosensor for urea. In the model solution which mimics blood serum, the urea-sensitive electrode has a detection limit of 10(-5) M urea and a maximum response of approximately 120 mV. The attractive performance characteristics are advantageous over those of existing pH sensors and offer great promise for sensing and biosensing applications.