Peri-implantitis Progression Around Thin Sputtered Hydroxyapatite-Coated Implants: Clinical and Radiographic Evaluation in Dogs
Peri-implantitis Progression Around Thin Sputtered Hydroxyapatite-Coated Implants: Clinical and Radiographic Evaluation in Dogs
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DOI：
10.11607/jomi.2891
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发表时间：
2013-05-01
影响因子：
2
通讯作者：
Kasugai, Shohei
中科院分区：
文献类型：
--
作者：
Madi, Marwa;Zakaria, Osama;Kasugai, Shohei
目的：评价薄溅射羟基磷灰石（HA）涂层种植体周围软组织和硬组织对实验性种植体周围炎的反应，并将其与其他表面处理的种植体的反应进行比较。材料与方法：采用机械加工(M)、喷砂/酸蚀（SA）、1 μ M薄溅射ha涂层(S)和等离子喷涂ha涂层(P)四种不同表面的48颗种植体植入6只beagle犬的下颌骨。3个月后，结扎诱导实验性种植体周围炎，使菌斑积累。在4个月的主动破裂期后，结扎被拆除，斑块积累持续5个月（进展期）。在基线、活动性破裂期后和进展期后评估x线片边缘骨水平、探探深度、临床附着水平和改良牙龈指数。结果：主动破裂后，所有种植体的平均探深和临床附着水平均显著增加，但在进展期无显著差异。放射学分析显示，在活跃破裂期间，边缘骨丢失1至1.7毫米。进一步的骨质流失发生在进展期（mm 0.2 mm, SA 0.3 mm, S 0.2 mm, P 0.4 mm）。结论：在种植体周围炎的情况下，种植体周围所有四个表面的组织行为都具有可比性。薄溅射ha涂层种植体具有磷酸钙涂层的良好骨导电性，在种植体周围炎的进展过程中不会进一步加剧种植体周围组织的破坏。
Purpose: Soft and hard tissue responses to experimental peri-implantitis around thin sputter hydroxyapatite (HA)-coated implants were evaluated and compared to the responses to implants with other surface treatments. Materials and Methods: Forty-eight dental implants with four different surfaces-machined (M), sandblasted/acid-etched (SA), 1-mu m thin sputter HA-coated (S), and plasma-sprayed HA-coated (P)-were inserted into the mandibles of six beagle dogs. Three months later, experimental peri-implantitis was induced with ligatures to allow plaque accumulation. After a 4-month period of active breakdown, the ligatures were removed, and plaque accumulation continued for 5 additional months (progression period). Radiographic marginal bone levels, probing depths, clinical attachment levels, and modified Gingival Index were evaluated at baseline, after the active breakdown period, and after the progression period. Results: Significant increases in mean probing depths and clinical attachment levels were seen around all implants after active breakdown, but no significant differences were found during the progression period. Radiographic analysis revealed marginal bone loss of 1 to 1.7 mm during the active breakdown period. Additional bone loss occurred during the progression period (M 0.2 mm, SA 0.3 mm, S 0.2 mm, P 0.4 mm). Conclusion: Comparable tissue behavior was demonstrated around dental implants with all four surfaces under peri-implantitis conditions. Thin sputter HA-coated implants possess the favorable osteoconductive properties of calcium phosphate coatings without exacerbating further peri-implant tissue breakdown during the progression of peri-implantitis.