Successful multimodal therapy for the metastasis of ascending colon after curative resection of esophageal cancer: a case report with long-term survival.
Successful multimodal therapy for the metastasis of ascending colon after curative resection of esophageal cancer: a case report with long-term survival.
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食管癌根治性切除术后升结肠转移的成功多模式治疗：长期生存的病例报告。
DOI：
10.1007/s12328-022-01728-z
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Furukawa H.
中科院分区：
文献类型：
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作者：
Uotani T;Tanemura M;Matsuda H;Matsumoto K;Higashi S;Nonaka R;Wakasugi M;Miyake M;Fujii T;Furukawa H.
摘要食道癌之孤立性结肠转移是罕见的。食管癌远处转移患者的预后极差。本文报告一例食管癌结肠转移经多模式治疗后长期存活的病例。一位67岁的男性被诊断为胸中段食管鳞状细胞癌。患者接受新辅助化疗，然后接受食管次全切除术。食管切除术后约1年，在食管癌的随访计算机断层扫描中检测到一个无症状的孤立性结肠肿块。术前结肠镜检查显示升结肠有一个5厘米的3型肿瘤，活检标本的组织学结果表明可能是原发性食管鳞状细胞癌的转移。患者接受腹腔镜回结肠切除术和D3淋巴结清扫术。组织学上，结肠肿瘤被证实是从食管鳞状细胞癌转移。据我们所知，只有8例切除孤立性结肠转移，包括本例，已被报道，本例食管切除术后生存超过3年。切除原发性食管癌的无症状孤立器官转移似乎是一个很好的治疗选择，即使在食管切除术后。
Solitary colonic metastasis from esophageal cancer is rare. The prognosis of patients with distant metastases from esophageal cancer is extremely poor. A case of long-term survival with colonic metastasis from esophageal cancer treated by multimodal therapy is reported. A 67-year-old man was diagnosed with middle thoracic esophageal squamous cell carcinoma. The patient received neoadjuvant chemotherapy and then underwent subtotal esophagectomy. Approximately 1 year after esophagectomy, an asymptomatic, solitary colonic mass was detected on the follow-up computed tomography for esophageal cancer. Preoperative colonoscopy showed a 5-cm type 3 tumor at the ascending colon, and histological findings of the biopsy specimen indicated possible metastasis from primary esophageal squamous cell carcinoma. The patient underwent laparoscopic ileocolic resection with D3 lymph noddle dissection. Histologically, the colonic tumor was confirmed to be a metastasis from the esophageal squamous cell carcinoma. To the best of our knowledge, only eight cases with resected solitary colonic metastasis, including the present case, have been reported, and the present patient achieved greater than 3-year survival after esophagectomy. Resection of an asymptomatic solitary organ metastasis from primary esophageal cancer appears to be a good therapeutic option, even following esophagectomy.