In vivo cartilage contact strains in patients with lateral ankle instability.
In vivo cartilage contact strains in patients with lateral ankle instability.
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DOI：
10.1016/j.jbiomech.2010.05.013
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发表时间：
2010-09-17
影响因子：
2.4
通讯作者：
DeFrate, Louis E.
中科院分区：
文献类型：
--
作者：
Bischof, Johanna E.;Spritzer, Charles E.;Caputo, Adam M.;Easley, Mark E.;DeOrio, James K.;Nunley, James A., II;DeFrate, Louis E.
踝关节扭伤时距腓前韧带（ATFL）和粗腓韧带（CFL）的损伤可能与骨关节炎的发生有关。这些患者的胫距运动学改变已被证实，但踝关节外侧不稳定（LAI）对体内软骨应变的影响尚未被描述。我们假设，峰值软骨应变增加，并在ATFL损伤的患者的位置是转移。我们使用3-D MRI模型和双平面荧光透视来评估7例单侧LAI患者体内软骨接触应变。受试者有慢性单侧ATFL损伤或ATFL和CFL联合损伤，并在踏上测力板时增加负荷进行评估。峰值软骨应变和峰值应变的位置进行了测量，使用对侧正常踝关节作为对照。踝关节LAI表现出显着增加峰值应变时，与ATFL完整的控制。例如，在100%体重时，损伤侧的峰值应变为29±8%，而完好侧为21±5%。损伤踝关节的峰值应变位置也表现出明显的前向平移和内侧平移。在100%体重时，损伤踝关节的峰值应变位置相对于完整踝关节向前平移15.5±7.1mm，向内平移12.9±4.3mm。这些变化对应于临床观察到的骨关节炎区域。慢性LAI，因此，可能有助于发展胫距软骨退变，由于改变软骨应变。
Damage to the anterior talofibular ligament (ATFL) and cacaneofibular ligament (CFL) during ankle sprain may be linked to the development of osteoarthritis. Altered tibiotalar kinematics have been demonstrated in these patients, but the effects of lateral ankle instability (LAI) on in vivo cartilage strains have not been described. We hypothesized that peak cartilage strains increase, and the location is shifted in patients with ATFL injuries. We used 3-D MRI models and biplanar fluoroscopy to evaluate in vivo cartilage contact strains in seven patients with unilateral LAI. Subjects had chronic unilateral ATFL injury or combined ATFL and CFL injury, and were evaluated with increasing load while stepping onto a force plate. Peak cartilage strain and the location of the peak strain were measured using the contralateral normal ankle as a control. Ankles with LAI demonstrated significantly increased peak strain when compared with ATFL-intact controls. For example, at 100% body weight, peak strain was 29±8% on the injured side compared to 21±5% on the intact side. The position of peak strain on the injured ankle also showed significant anterior translation and medial translation. At 100% body weight, the location of peak strain in the injured ankle translated anteriorly by 15.5±7.1mm and medially by 12.9±4.3mm relative to the intact ankle. These changes correspond to the region of clinically-observed osteoarthritis. Chronic LAI, therefore, may contribute to the development of tibiotalar cartilage degeneration due to altered cartilage strains.
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影响因子：
1.7
作者：
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通讯作者：
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DOI：
10.1097/01.blo.0000197079.26600.09
发表时间：
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