Granulocyte collection efficiency and yield are enhanced by the use of a higher interface offset during apheresis of donors given granulocyte‐ colony‐stimulating factor
Granulocyte collection efficiency and yield are enhanced by the use of a higher interface offset during apheresis of donors given granulocyte‐ colony‐stimulating factor
复制标题
在给予粒细胞集落刺激因子的供体的单采过程中，通过使用更高的界面偏移来提高粒细胞收集效率和产量
作者：
Douglas Adkins;Suhail Ali;G. Despotis;M. Dynis;Lawrence T. Goodnough
背景：评估粒细胞输注治疗发热性中性粒细胞减少症的试验显示出不同的临床结果，部分原因可能是由于输注成分的中性粒细胞剂量较低。为了优化后一个变量，在给予粒细胞集落刺激因子（G-CSF）的正常供体中确定了单采过程中各种界面偏移（IO）设置对粒细胞收集效率（GCE）和产量的影响。
BACKGROUND: Trials evaluating granulocyte transfusions for therapy of febrile neutropenia demonstrated mixed clinical results, which may in part be due to the low neutrophil cell dose of the transfused components. To optimize the latter variable, the effect of various interface offset (IO) settings during apheresis on granulocyte collection efficiency (GCE) and yield was determined in normal donors given granulocyte‐colony‐stimulating factor (G‐CSF).
发热性粒细胞减少症患者的过滤与重力白细胞去除术：一项随机前瞻性试验。
影响因子：
20.3
作者：
Ambinder,EP;Button,GR;Cheung,T;Goldberg,JD;Holland,JF
通讯作者：
Holland,JF
针对已记录感染的治疗性粒细胞输注。
影响因子：
39.2
作者：
Winston,DJ;Ho,WG;Gale,RP
通讯作者：
Gale,RP