CLUSTERED TRANSFER-RNA GENES IN SCHIZOSACCHAROMYCES-POMBE CENTROMERIC DNA-SEQUENCE REPEATS
CLUSTERED TRANSFER-RNA GENES IN SCHIZOSACCHAROMYCES-POMBE CENTROMERIC DNA-SEQUENCE REPEATS
复制标题
DOI：
10.1073/pnas.88.4.1306
复制
发表时间：
1991-02-01
影响因子：
11.1
通讯作者：
CARBON, J
中科院分区：
文献类型：
--
作者：
KUHN, RM;CLARKE, L;CARBON, J
发现粟酒裂殖酵母染色体I和II的着丝粒相关的B'和B DNA序列重复含有tRNA基因簇。 着丝粒II区（cen2）包括至少22个tRNA基因，分布在含有指定tRNA（Ile）、tRNA（Ala）和tRNA（瓦尔）的基因的B序列重复的5个拷贝中。 单个B重复序列与其他tRNA基因有不同的关联，包括指定tRNA（Lys）、tRNA（Arg）和tRNA 2（Glu）的基因。 着丝粒I区（cen1）在B'重复元件的两个拷贝中含有至少6个tRNA基因，包括指定tRNA（Ile）、tRNA（Ala）和tRNA 3（Glu）的基因。 多个串联排列的tRNA基因簇可能是保守的，由于限制重组频率在着丝粒区域。
The centromere-associated B' and B DNA sequence repeats of Schizosaccharomyces pombe chromosomes I and II have been found to contain clusters of tRNA genes. The centromere II region (cen2) includes at least 22 tRNA genes distributed among five copies of the B sequence repeat containing genes specifying tRNA(Ile), tRNA(Ala), and tRNA(Val). Individual B repeats are variously associated with other tRNA genes, including those specifying tRNA(Lys), tRNA(Arg), and tRNA2(Glu). The centromere I region (cen1) contains at least six tRNA genes in two copies of the B' repeated element, including genes specifying tRNA(Ile), tRNA(Ala), and tRNA3(Glu). Multiple tandemly arranged clusters of tRNA genes are presumably conserved due to restricted recombination frequencies in the centromere regions.