Molecular mechanisms underlying sex pheromone production in the silkmoth, Bombyx mori:: Characterization of the molecular components involved in bombykol biosynthesis
Molecular mechanisms underlying sex pheromone production in the silkmoth, Bombyx mori:: Characterization of the molecular components involved in bombykol biosynthesis
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DOI：
10.1016/j.jinsphys.2007.02.014
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发表时间：
2007-08-01
影响因子：
2.2
通讯作者：
Fonagy, Adrien
中科院分区：
文献类型：
--
作者：
Matsumoto, Shogo;Hull, J. Joe;Fonagy, Adrien
许多种雌蛾产生性信息素来吸引同种雄蛾。迄今为止，已经从570多种蛾类中鉴定出性信息素。大多数蛾类利用I型信息素，其由长度为10-18个碳的直链化合物组成，具有伯醇、醛或乙酸酯的官能团，并且通常具有几个双键。相反，一些蛾类物种使用不饱和烃或烃环氧化物作为性信息素，这些不饱和烃或烃环氧化物被分类为11型鳞翅目信息素。过去30年的研究表明，雌蛾通常以多组分混合物的形式产生性信息素，其中各个组分的比例得到精确控制，从而有可能产生物种特异性信息素混合物。至于I型信息素的生物合成，已经确定它们是通过脂肪酸生物合成途径的修饰在信息素腺（PG）中从头合成的。然而，PG细胞内的许多分子组分（即，酶、蛋白质和小的调节分子）尚未被功能性地表征，PG细胞中性信息素产生的分子机制仍然知之甚少。为了解决这个问题，我们最近的特点，一些分子参与的生物合成的性信息素bombykol在家蚕，家蚕。这些和其他关键分子的表征将有助于我们理解鳞翅目昆虫性信息素产生的确切机制。(C)2007爱思唯尔有限公司版权所有。
Many species of female moths produce sex pheromones to attract conspecific males. To date, sex pheromones from more than 570 moth species have been chemically identified. Most moth species utilize Type I pheromones that consist of straight-chain compounds 10-18 carbons in length with a functional group of a primary alcohol, aldehyde, or acetate ester and usually with several double bonds. In contrast, some moth species use unsaturated hydrocarbons or hydrocarbon epoxides, classified as Type 11 lepidopteran pheromones, as sex pheromones. Studies over the past three decades have demonstrated that female moths usually produce sex pheromones as multicomponent blends where the ratio of the individual components is precisely controlled, thus making it possible to generate species-specific pheromone blends. As for the biosynthesis of Type I pheromones, it is well established that they are de novo synthesized in the pheromone gland (PG) through modifications of fatty acid biosynthetic pathways. However, as many of the molecular components within the PG cells (i.e., enzymes, proteins, and small regulatory molecules) have not been functionally characterized, the molecular mechanisms underlying sex pheromone production in PG cells remain poorly understood. To address this, we have recently characterized some of the molecules involved in the biosynthesis of the sex pheromone bombykol in the silkmoth, Bombyx mori. Characterization of these, and other, key molecules will facilitate our understanding of the precise mechanisms underlying lepidopteran sex pheromone production. (C) 2007 Elsevier Ltd. All rights reserved.