Contrast enhanced MR venography with gadofosveset trisodium: evaluation of the intracranial and extracranial venous system.
Contrast enhanced MR venography with gadofosveset trisodium: evaluation of the intracranial and extracranial venous system.
复制标题
钆磷维三钠对比增强磁共振静脉造影：颅内和颅外静脉系统的评估。
DOI：
10.1002/jmri.24409
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Wolinsky,JerryS
中科院分区：
文献类型：
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作者：
Kramer,LarryA;Cohen,AlanM;Hasan,KhaderM;Heimbigner,JaredH;Barreto,AndrewD;Brod,StaleyA;Narayana,PonnadaA;Wolinsky,JerryS
目的验证Gadofosveset三钠对比增强磁共振静脉成像(CEMRV)在颅内外静脉系统综合评价中的有效性。材料与方法在一项机构审查委员会批准的、符合HIPAA标准的99例CEMRV研究中，评估了临时信号衰减、平面内饱和和血流伪影。在39名受试者中，颈内静脉(IJ)、头臂静脉和奇静脉的内径狭窄百分比按照导管静脉造影(CV)和磁共振血管造影(CEMRV)的下列顺序进行编码：0级 ≤ 50%、1级50%和 ≤ 75%、2级75%和100%和3级 = 100%，并与在CV上获得的压力梯度进行比较。所有的头臂静脉和奇静脉在两种情况下都匹配0级狭窄。甲状腺水平的IJ静脉有15%的 ≥ -1级狭窄，而CV及以下的IJ静脉为4%，其中5%的IJ静脉 ≥ -1级狭窄，而CV为20%。在所有编码静脉的联合数据集中，狭窄程度的不同模式之间有较好的一致性(κ = 0.24)。结论使用Gadofosveset trondium进行CEMRV对静脉系统的评估是准确的。雷森。影像2014；40：630-640。©2013 Wiley期刊，Inc.
PurposeTo demonstrate the efficacy of contrast enhanced magnetic resonance venography (CEMRV) using gadofosveset trisodium in the comprehensive evaluation of the intracranial and extracranial venous system.Materials and MethodsTemporal signal decay, in‐plane saturation and flow artifacts were assessed in an institutional review board approved, HIPAA compliant CEMRV study of 99 subjects. In a 39 subject subset, percent diameter narrowing of the internal jugular (IJ), brachiocephalic and azygous veins were coded according to the following ordinal grades for both catheter venography (CV) and CEMRV: grade 0 ≤ 50%, grade 1 >50% and ≤ 75%, grade 2 >75% and <100% and grade 3 = 100% and compared with pressure gradient measurements obtained during CV.ResultsThere was no significant signal decay, in‐plane saturation or flow artifacts identified on CEMRV or hemodynamically significant pressure gradients identified on CV. All brachiocephalic and azygous veins had matched grade 0 narrowing on both modalities. Discrepancy between modalities occurred in the IJ veins at the level of thyroid gland where 15% of IJ veins had CEMRV grade ≥ 1 narrowing compared with 4% for CV or below the thyroid gland where 5% of IJ veins had CEMRV grade ≥ 1 narrowing compared with 20% for CV. There was fair agreement (κ = 0.24) between modalities for grade of narrowing in the combined data set of all coded veins.ConclusionCEMRV using gadofosveset trisodium is accurate in the evaluation of the venous system.J. Magn. Reson. Imaging 2014;40:630–640. ©2013 Wiley Periodicals, Inc.