The synthesis of nitrogen-doped carbon nanotubes/gold composites and their application to the detection of thioridazine
The synthesis of nitrogen-doped carbon nanotubes/gold composites and their application to the detection of thioridazine
复制标题
氮掺杂碳纳米管/金复合材料的合成及其在硫利达嗪检测中的应用
DOI：
10.1007/s10008-012-1672-0
复制
发表时间：
2012-08-01
影响因子：
2.5
通讯作者：
Hou, Wenhua
中科院分区：
文献类型：
--
作者：
Feng, Xiaomiao;Wang, Chen;Hou, Wenhua
通过简单的自组装方法制备了氮掺杂碳纳米管（N-CNTs）/金复合材料。通过透射电子显微镜、扫描电子显微镜、X射线衍射、拉曼光谱、紫外-可见吸收光谱和X射线光电子能谱等手段对复合材料的形貌、组成和光学性能进行了研究。这种纳米复合材料结合了纳米碳管和金纳米粒子的优点，显示出许多优异的性能，如良好的水溶性和令人满意的生物相容性。循环伏安实验表明，纳米碳管/金复合材料具有较高的导电性。在此基础上，将纳米碳管/金修饰电极成功地应用于盐酸硫利达嗪（TH）的伏安测定。TH传感器的线性范围为12 ~ 850 μM，检测限为1.3 μM，信噪比为3，长期稳定，重现性好。
Nitrogen-doped carbon nanotubes (N-CNTs)/gold composites were synthesized through a simple self-assembly method. The morphology, composition, and optical properties of the resulted composites were investigated by transmission electron microscopy, scanning electron microscopy, X-ray diffraction, Raman spectra, ultraviolet–visible absorption spectrum, and X-ray photoelectron spectroscopic. This nanocomposite combines the advantages of N-CNTs and gold nanoparticales showing many excellent properties such as good dispersibility in water and satisfactory biocompatibility. Cyclic voltammogram experiment shows that N-CNTs/gold composite has high conductivity. Based on these aspects, N-CNTs/gold-modified electrode was applied to the voltammetric determination of thioridazine hydrochloride (TH) successfully. The linear calibration range for the TH sensor was 12 ~ 850 μM with a detection limit of 1.3 μM at a signal-to-noise ratio of 3, long-term stability, and good reproducibility.